8-phenyltheophylline has been researched along with Hyperemia in 20 studies
8-phenyltheophylline: purinergic P1 receptor antagonist
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether retinal blood flow increases in response to perinatal hypoglycemia and whether the vasodilator adenosine is involved in mediating the hyperemic response." | 7.69 | Hypoglycemic hyperemia in retina of newborn pigs. Involvement of adenosine. ( Gidday, JM; Zhu, Y, 1996) |
| "To explore a possible role for adenosine in the pathogenesis of the splanchnic hyperemia of cirrhosis, we administered 8-phenyltheophylline, a specific adenosine receptor antagonist, to rats with biliary cirrhosis caused by bile duct ligation and to control sham-operated rats." | 7.68 | Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats. ( Chilton, EL; Lee, SS; Pak, JM, 1992) |
| "Intestinal reactive hyperemia is an abrupt blood flow increase following release from anterior mesenteric arterial occlusion." | 5.29 | Adenosine modulates reactive hyperemia in rat gut. ( Hottenstein, OD; Jacobson, ED; Palen, TE; Pawlik, T; Pawlik, WW, 1993) |
| " Here we tested the hypothesis that K(V) channels participate in coronary reactive hyperemia and examined the role of K(V) channels in responses to nitric oxide (NO) and adenosine, two putative mediators." | 3.74 | Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation. ( Borbouse, L; Bratz, IN; Dick, GM; Dincer, UD; Knudson, JD; Payne, GA; Rogers, PA; Tune, JD, 2008) |
| "To determine whether retinal blood flow increases in response to perinatal hypoglycemia and whether the vasodilator adenosine is involved in mediating the hyperemic response." | 3.69 | Hypoglycemic hyperemia in retina of newborn pigs. Involvement of adenosine. ( Gidday, JM; Zhu, Y, 1996) |
| "To explore a possible role for adenosine in the pathogenesis of the splanchnic hyperemia of cirrhosis, we administered 8-phenyltheophylline, a specific adenosine receptor antagonist, to rats with biliary cirrhosis caused by bile duct ligation and to control sham-operated rats." | 3.68 | Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats. ( Chilton, EL; Lee, SS; Pak, JM, 1992) |
| "In pentobarbital sodium-anesthetized dogs we investigated the role of the endothelium-derived nitric oxide and adenosine in the regulation of the coronary blood flow during myocardial reactive hyperemia." | 3.68 | Role of endothelium-derived nitric oxide in myocardial reactive hyperemia. ( Ishizaka, H; Okumura, K; Tsuchiya, T; Yamabe, H; Yasue, H, 1992) |
| "Adenosine has been postulated to mediate the increase in coronary blood flow when myocardial oxygen consumption is increased." | 1.30 | Role of adenosine in local metabolic coronary vasodilation. ( Feigl, EO; Kroll, K; Richmond, KN; Van Bibber, R; Yada, T, 1999) |
| "Intestinal reactive hyperemia is an abrupt blood flow increase following release from anterior mesenteric arterial occlusion." | 1.29 | Adenosine modulates reactive hyperemia in rat gut. ( Hottenstein, OD; Jacobson, ED; Palen, TE; Pawlik, T; Pawlik, WW, 1993) |
| "In the early phase of reactive hyperemia, all arterial microvessels dilated, and the magnitude of peak dilation was greater in vessels smaller than 100 microns compared with those larger than 100 microns." | 1.28 | Microvascular sites and mechanisms responsible for reactive hyperemia in the coronary circulation of the beating canine heart. ( Akai, K; Ashikawa, K; Kanatsuka, H; Komaru, T; Sato, K; Sekiguchi, N; Takishima, T; Wang, Y, 1992) |
| "1." | 1.28 | The role of adenosine in the hyperaemic response of the hepatic artery to portal vein occlusion (the 'buffer response'). ( Alexander, B; Mathie, RT, 1990) |
| "Hyperemia was quantitated from the peak vasodilation and from the area under the flow-hyperemia curve." | 1.27 | Vascular escape from vasoconstriction and post-stimulatory hyperemia in the superior mesenteric artery of the cat. ( Lautt, WW; Legare, DJ; Lockhart, LK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 15 (75.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dick, GM | 1 |
| Bratz, IN | 1 |
| Borbouse, L | 1 |
| Payne, GA | 1 |
| Dincer, UD | 1 |
| Knudson, JD | 1 |
| Rogers, PA | 1 |
| Tune, JD | 1 |
| Yada, T | 2 |
| Hiramatsu, O | 1 |
| Kimura, A | 1 |
| Tachibana, H | 1 |
| Chiba, Y | 1 |
| Lu, S | 1 |
| Goto, M | 1 |
| Ogasawara, Y | 1 |
| Tsujioka, K | 1 |
| Kajiya, F | 1 |
| Chłopicki, S | 1 |
| Gryglewski, RJ | 2 |
| Duncker, DJ | 2 |
| van Zon, NS | 1 |
| Pavek, TJ | 1 |
| Herrlinger, SK | 1 |
| Bache, RJ | 2 |
| Pawlik, WW | 1 |
| Hottenstein, OD | 1 |
| Palen, TE | 1 |
| Pawlik, T | 1 |
| Jacobson, ED | 1 |
| Zhu, Y | 1 |
| Gidday, JM | 1 |
| Poucher, SM | 2 |
| Chlopicki, S | 1 |
| Niezabitowski, P | 1 |
| Jakubowski, A | 1 |
| Lomnicka, M | 1 |
| Otomo, J | 1 |
| Nozaki, N | 1 |
| Tomoike, H | 1 |
| Ishibashi, Y | 1 |
| Zhang, J | 1 |
| Richmond, KN | 1 |
| Van Bibber, R | 1 |
| Kroll, K | 1 |
| Feigl, EO | 1 |
| Kanatsuka, H | 1 |
| Sekiguchi, N | 1 |
| Sato, K | 1 |
| Akai, K | 1 |
| Wang, Y | 1 |
| Komaru, T | 1 |
| Ashikawa, K | 1 |
| Takishima, T | 1 |
| Lee, SS | 1 |
| Chilton, EL | 1 |
| Pak, JM | 1 |
| Yamabe, H | 1 |
| Okumura, K | 1 |
| Ishizaka, H | 1 |
| Tsuchiya, T | 1 |
| Yasue, H | 1 |
| Mathie, RT | 1 |
| Alexander, B | 1 |
| Nowell, CG | 1 |
| Collis, MG | 1 |
| Jeremy, RW | 1 |
| Stahl, L | 1 |
| Gillinov, M | 1 |
| Litt, M | 1 |
| Aversano, TR | 1 |
| Becker, LC | 1 |
| Hina, K | 1 |
| Watanabe, H | 1 |
| Ueeda, M | 1 |
| Yamada, N | 1 |
| Saito, D | 1 |
| Haraoka, S | 1 |
| Tsuji, T | 1 |
| Kusachi, S | 1 |
| Lautt, WW | 2 |
| Legare, DJ | 1 |
| Lockhart, LK | 1 |
1 review available for 8-phenyltheophylline and Hyperemia
| Article | Year |
|---|---|
ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Dogs; Enzyme Inhibit | 1998 |
19 other studies available for 8-phenyltheophylline and Hyperemia
| Article | Year |
|---|---|
Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.
Topics: 4-Aminopyridine; Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors | 2008 |
Direct in vivo observation of subendocardial arteriolar response during reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyb | 1995 |
Nitric oxide is a major mediator in reactive hyperaemia evoked by a brief coronary occlusion in the guinea pig heart.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Coronary Vessels; Fema | 1993 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyper | 1995 |
Adenosine modulates reactive hyperemia in rat gut.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Blood Pressure; Hyperemia; Intestines; | 1993 |
Hypoglycemic hyperemia in retina of newborn pigs. Involvement of adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Blood Glucose; Blood Pressure; Fluorescein Angiography; Hypere | 1996 |
The role of the A(2A) adenosine receptor subtype in functional hyperaemia in the hindlimb of anaesthetized cats.
Topics: Adenosine; Animals; Arteries; Cats; Gases; Hindlimb; Hydrogen-Ion Concentration; Hyperemia; Isometri | 1996 |
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase I | 1996 |
Roles of nitric oxide and adenosine in the regulation of coronary conductance in the basal state and during reactive hyperemia.
Topics: Adenosine; Animals; Coronary Circulation; Enzyme Inhibitors; Hyperemia; In Vitro Techniques; NG-Nitr | 1997 |
Role of adenosine in local metabolic coronary vasodilation.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Electrocardiography; Heart Rate; H | 1999 |
Microvascular sites and mechanisms responsible for reactive hyperemia in the coronary circulation of the beating canine heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vess | 1992 |
Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats.
Topics: Adenosine; Animals; Hemodynamics; Hyperemia; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental | 1992 |
Role of endothelium-derived nitric oxide in myocardial reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Dogs; Drug Combinations; Endot | 1992 |
The role of adenosine in the hyperaemic response of the hepatic artery to portal vein occlusion (the 'buffer response').
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dog | 1990 |
The role of adenosine in exercise hyperaemia of the gracilis muscle in anaesthetized cats.
Topics: Adenosine; Animals; Cats; Hyperemia; Leg; Muscle Contraction; Muscles; Physical Exertion; Regional B | 1990 |
Preservation of coronary flow reserve in stunned myocardium.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Female; Hyperemia; Male; Myocardial Reperfusion; Myo | 1989 |
Forskolin potentiates myocardial reactive hyperaemia in the open chest dog: the contribution of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Hemo | 1989 |
Vascular escape from vasoconstriction and post-stimulatory hyperemia in the superior mesenteric artery of the cat.
Topics: Adenosine; Animals; Cats; Electric Stimulation; Female; Hyperemia; Male; Mesenteric Arteries; Norepi | 1988 |
Effect of raised portal venous pressure and postocclusive hyperemia on superior mesenteric arterial resistance in control and adenosine receptor blocked state in cats.
Topics: Animals; Blood Pressure; Cats; Electric Stimulation; Female; Hyperemia; Liver; Male; Mesenteric Arte | 1986 |