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8-phenyltheophylline and Heart Disease, Ischemic

8-phenyltheophylline has been researched along with Heart Disease, Ischemic in 15 studies

8-phenyltheophylline: purinergic P1 receptor antagonist

Research Excerpts

ExcerptRelevanceReference
"Persisting coronary vasoconstrictor tone that is responsive to exogenous adenosine administration has been demonstrated during myocardial ischemia."7.68Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. ( Bache, RJ; Homans, DC; Laxson, DD, 1993)
"Persisting coronary vasoconstrictor tone that is responsive to exogenous adenosine administration has been demonstrated during myocardial ischemia."3.68Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. ( Bache, RJ; Homans, DC; Laxson, DD, 1993)
"We conclude that 1) in sustained myocardial ischemia, SOD treatment attenuates ischemic injury caused by coronary microembolization by restoration of 5'-nucleotidase activity and augmentation of adenosine release; 2) this beneficial effect of SOD is observed even after coronary microembolization; and 3) the beneficial effects of SOD are attributable to coronary vasodilation produced by augmented adenosine release."3.68Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization. ( Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Sato, H; Takashima, S, 1993)
"To test the hypothesis that the endothelium-derived relaxing factor (EDRF) contributes to coronary vasodilation induced by myocardial ischemia, we examined the effect of NG-nitro-L-arginine (a potent and selective inhibitor of EDRF release) on the coronary reactive hyperemic response in the open-chest dogs."3.68NG-nitro-L-arginine attenuates flow debt repayment in the reactive hyperemic response of the open-chest dog coronary artery: contribution of endothelium-derived relaxing factor. ( Kajikawa, Y; Kusachi, S; Marutani, M; Tsuji, T; Yamasaki, S, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (93.33)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Minamino, T1
Kitakaze, M2
Morioka, T1
Node, K1
Shinozaki, Y1
Chujo, M1
Mori, H1
Takeda, H1
Inoue, M2
Hori, M3
Rynning, SE1
Brunvand, H1
Birkeland, S1
Hexeberg, E1
Grong, K1
Hoshida, S1
Kuzuya, T1
Nishida, M1
Yamashita, N1
Oe, H1
Kamada, T2
Tada, M1
Laxson, DD2
Homans, DC1
Bache, RJ2
Duncker, DJ1
Lindstrom, P1
Urabe, K1
Miura, T2
Iwamoto, T1
Ogawa, T1
Goto, M1
Sakamoto, J2
Iimura, O1
Takashima, S1
Sato, H1
Bouchard, JF1
Lamontagne, D1
Gryglewski, RJ1
Chlopicki, S1
Niezabitowski, P1
Jakubowski, A1
Lomnicka, M1
Askenasy, N1
Navon, G1
Ismail, JA1
McDonough, KH1
Miki, T1
Bünger, R1
Suzuki, K1
Shimamoto, K1
Schreieck, J1
Richardt, G1
Yamamoto, M1
Egashira, K1
Arimura, K1
Tada, H1
Shimokawa, H1
Takeshita, A1
Marutani, M1
Kusachi, S1
Kajikawa, Y1
Yamasaki, S1
Tsuji, T1

Other Studies

15 other studies available for 8-phenyltheophylline and Heart Disease, Ischemic

ArticleYear
Bidirectional effects of aminophylline on myocardial ischemia.
    Circulation, 1995, Sep-01, Volume: 92, Issue:5

    Topics: Adenosine; Aminophylline; Animals; Coronary Circulation; Dogs; Heart; Lactates; Lactic Acid; Myocard

1995
Endogenous adenosine attenuates myocardial stunning by antiadrenergic effects exerted during ischemia and not during reperfusion.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:3

    Topics: Adenosine; Animals; Cats; Coronary Circulation; Doxazosin; Heart; Hemodynamics; Male; Myocardial Con

1995
Adenosine blockade during reperfusion reverses the infarct limiting effect in preconditioned canine hearts.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Animals; Dogs; Female; Leukocyte Count; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium

1994
Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dog

1993
Endogenous adenosine and coronary vasoconstriction in hypoperfused myocardium during exercise.
    Cardiovascular research, 1993, Volume: 27, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Coronary Ves

1993
Preconditioning enhances myocardial resistance to postischaemic myocardial stunning via adenosine receptor activation.
    Cardiovascular research, 1993, Volume: 27, Issue:4

    Topics: Animals; Disease Models, Animal; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reper

1993
Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization.
    Circulation, 1993, Volume: 87, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Animals; Coronary Circulation; Dogs; Embolism; Injections; Lactates; Lac

1993
Mechanisms of protection afforded by preconditioning to endothelial function against ischemic injury.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Endothelium, Vascular; Glyburide; In Vitro Techni

1996
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
    Physiological research, 1996, Volume: 45, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase I

1996
Intermittent ischemia: energy metabolism, cellular volume regulation, adenosine and insights into preconditioning.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:6

    Topics: Adenosine; Animals; Cell Size; Creatine; Energy Metabolism; Glyburide; Glycogen; Glycolysis; In Vitr

1997
The role of coronary flow and adenosine in postischemic recovery of septic rat hearts.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Animals; Bacteremia; Blood Pressure; Coronary Circulation; Escherichia coli Infections; Heart Rate;

1998
Ecto-5'-nucleotidase is not required for ischemic preconditioning in rabbit myocardium in situ.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Pressure; Enzyme Inh

1998
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiogra

1999
Coronary vascular K+ATP channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure.
    Japanese circulation journal, 2000, Volume: 64, Issue:9

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relatio

2000
NG-nitro-L-arginine attenuates flow debt repayment in the reactive hyperemic response of the open-chest dog coronary artery: contribution of endothelium-derived relaxing factor.
    Acta medica Okayama, 1992, Volume: 46, Issue:5

    Topics: Adenosine; Animals; Arginine; Coronary Vessels; Dogs; Myocardial Ischemia; Nitric Oxide; Nitroargini

1992