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8-phenyltheophylline and Coronary Disease

8-phenyltheophylline has been researched along with Coronary Disease in 12 studies

8-phenyltheophylline: purinergic P1 receptor antagonist

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The role of adenosine as a mediator of the bradycardia associated with graded global ischaemia in rat heart was examined."7.67Mediation by adenosine of bradycardia in rat heart during graded global ischaemia. ( Headrick, J; Willis, RJ, 1988)
"The role of adenosine as a mediator of the bradycardia associated with graded global ischaemia in rat heart was examined."3.67Mediation by adenosine of bradycardia in rat heart during graded global ischaemia. ( Headrick, J; Willis, RJ, 1988)
"When adenosine release was attenuated by administration of prazosin (4 micrograms/kg/min i."1.28Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium. ( Hori, M; Inoue, M; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H; Takashima, S, 1992)
"Propranolol was infused into the bypass tube to exclude the metabolic effects of norepinephrine."1.28Beneficial effects of alpha 2-adrenoceptor activity on ischemic myocardium during coronary hypoperfusion in dogs. ( Gotoh, K; Hori, M; Inoue, M; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's7 (58.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fang, HK1
Sturgeon, C1
Segil, LJ1
Ripper, RL1
Law, WR1
Ishibashi, Y1
Duncker, DJ1
Zhang, J1
Bache, RJ1
Sato, H4
Hori, M4
Kitakaze, M4
Takashima, S2
Inoue, M4
Kitabatake, A4
Kamada, T4
Miura, T1
Ogawa, T1
Iwamoto, T1
Shimamoto, K1
Iimura, O1
Gotoh, K2
Iwai, K1
Iwakura, K2
Koretsune, Y1
Angello, DA1
Headrick, JP2
Coddington, NM1
Berne, RM1
Willis, RJ2
Hina, K1
Watanabe, H1
Ueeda, M1
Yamada, N1
Saito, D1
Haraoka, S1
Tsuji, T1
Kusachi, S1
Headrick, J1
Richardt, G1
Waas, W1
Kranzhöfer, R1
Mayer, E1
Schömig, A1

Reviews

1 review available for 8-phenyltheophylline and Coronary Disease

ArticleYear
ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise.
    Circulation research, 1998, Feb-23, Volume: 82, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Dogs; Enzyme Inhibit

1998

Other Studies

11 other studies available for 8-phenyltheophylline and Coronary Disease

ArticleYear
Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 2

    Topics: Adenosine; Animals; Coronary Disease; Dogs; Glucose; Glycolysis; Hemodynamics; Iodoacetates; Iodoace

1997
Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium.
    Circulation, 1992, Volume: 85, Issue:4

    Topics: Adenosine; Animals; Coronary Disease; Dogs; Heart; Isoproterenol; Myocardial Contraction; Prazosin;

1992
Dipyridamole potentiates the myocardial infarct size-limiting effect of ischemic preconditioning.
    Circulation, 1992, Volume: 86, Issue:3

    Topics: Adaptation, Physiological; Animals; Coronary Disease; Dipyridamole; Hemodynamics; Male; Myocardial I

1992
Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs.
    Circulation research, 1991, Volume: 69, Issue:5

    Topics: Adenosine; Animals; Blood Pressure; Bucladesine; Colforsin; Coronary Circulation; Coronary Disease;

1991
Role of oxygen-derived free radicals in myocardial edema and ischemia in coronary microvascular embolization.
    Circulation, 1991, Volume: 84, Issue:2

    Topics: Allopurinol; Animals; Ascorbic Acid; Body Water; Cardiomyopathies; Coronary Disease; Dogs; Edema; Em

1991
Adenosine antagonism decreases metabolic but not functional recovery from ischemia.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Heart; Hemodynamics; Male; Myocardium;

1991
Beneficial effects of alpha 2-adrenoceptor activity on ischemic myocardium during coronary hypoperfusion in dogs.
    Circulation research, 1989, Volume: 65, Issue:6

    Topics: Acidosis; Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Disease; Cyc

1989
Effects of adenosine antagonism and beta-blockade during low-flow ischaemia in rat heart.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:11

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catecholamines; Coronary Disease; H

1989
Forskolin potentiates myocardial reactive hyperaemia in the open chest dog: the contribution of adenylate cyclase.
    Cardiovascular research, 1989, Volume: 23, Issue:2

    Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Hemo

1989
Mediation by adenosine of bradycardia in rat heart during graded global ischaemia.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 412, Issue:6

    Topics: Adenosine; Animals; Atrioventricular Node; Bradycardia; Coronary Disease; Heart Rate; In Vitro Techn

1988
Adenosine inhibits exocytotic release of endogenous noradrenaline in rat heart: a protective mechanism in early myocardial ischemia.
    Circulation research, 1987, Volume: 61, Issue:1

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Coronary Disease; Di

1987