8-phenyltheophylline has been researched along with Acute Kidney Injury in 6 studies
8-phenyltheophylline: purinergic P1 receptor antagonist
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is concluded that the pharmacokinetic properties of 8-PT are likely to complicate its use in-vivo." | 1.28 | Pharmacokinetics of 8-phenyltheophylline in the rat. ( Bowmer, CJ; Collis, MG; Wormald, A; Yates, MS, 1989) |
| "Hydrochlorothiazide treatment compared with vehicle treatment did not ameliorate any index of renal function but resulted in significant elevations in plasma urea and creatinine levels." | 1.27 | Effect of 8-phenyltheophylline, enprofylline and hydrochlorothiazide on glycerol-induced acute renal failure in the rat. ( Bowmer, CJ; Collis, MG; Kellett, R; Yates, MS, 1987) |
| "glycerol was significantly greater in rats dosed i." | 1.27 | Effect of the adenosine antagonist 8-phenyltheophylline on glycerol-induced acute renal failure in the rat. ( Bowmer, CJ; Collis, MG; Yates, MS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, F | 1 |
| Shimada, J | 1 |
| Mizumoto, H | 1 |
| Karasawa, A | 1 |
| Kubo, K | 1 |
| Nonaka, H | 1 |
| Ishii, A | 1 |
| Kawakita, T | 1 |
| Wormald, A | 1 |
| Bowmer, CJ | 5 |
| Yates, MS | 5 |
| Collis, MG | 5 |
| Kellett, R | 2 |
6 other studies available for 8-phenyltheophylline and Acute Kidney Injury
| Article | Year |
|---|---|
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligan | 1992 |
Pharmacokinetics of 8-phenyltheophylline in the rat.
Topics: Acute Kidney Injury; Animals; Chromatography, High Pressure Liquid; Female; Half-Life; Injections, I | 1989 |
Effect of 8-phenyltheophylline, enprofylline and hydrochlorothiazide on glycerol-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Bronchodilator Agents; Creatinine; Glycerol; Hydrochlorothiazide; Inul | 1987 |
Amelioration of glycerol-induced acute renal failure in the rat with 8-phenyltheophylline: timing of intervention.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Glycerol; Inulin; Kidney; Male; Rats; | 1988 |
Effect of alkylxanthines on gentamicin-induced acute renal failure in the rat.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Creatinine; Gentamicins; Kidney; Male; Organ Si | 1988 |
Effect of the adenosine antagonist 8-phenyltheophylline on glycerol-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenosine; Animals; Creatinine; Glycerol; Heart Rate; Inulin; Kidney; Male; Org | 1986 |