Compounds > 8-oxo-7-8-dihydrodeoxyguanine

8-oxo-7-8-dihydrodeoxyguanine and Colonic-Polyps

8-oxo-7-8-dihydrodeoxyguanine has been researched along with Colonic-Polyps* in 1 studies

Other Studies

1 other study(ies) available for 8-oxo-7-8-dihydrodeoxyguanine and Colonic-Polyps

Article	Year
Age-associated increase of 8-hydroxydeoxyguanosine in human colorectal tissue DNA. The journals of gerontology. Series A, Biological sciences and medical sciences, 2001, Volume: 56, Issue:11 To clarify the role of oxidative stress in aging of colorectal tissue, we analyzed the 8-hydroxydeoxyguanosine (8-OH-dG) levels in colorectal biopsy samples from normal tissue of patients with either colorectal cancer (n = 15) or benign colorectal polyps (n = 40). An age-associated increase of 8-OH-dG was observed (p =.002), although the 8-OH-dG levels were not significantly different between the patients with cancer and those with polyps. These results suggest an increased level of 8-OH-dG formation in human colorectal tissue with age. Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Aging; Colon; Colonic Polyps; Colorectal Neoplasms; DNA; Guanine; Humans; Intestinal Polyps; Middle Aged; Oxidative Stress; Rectum	2001

Article

Year

Age-associated increase of 8-hydroxydeoxyguanosine in human colorectal tissue DNA.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2001, Volume: 56, Issue:11

To clarify the role of oxidative stress in aging of colorectal tissue, we analyzed the 8-hydroxydeoxyguanosine (8-OH-dG) levels in colorectal biopsy samples from normal tissue of patients with either colorectal cancer (n = 15) or benign colorectal polyps (n = 40). An age-associated increase of 8-OH-dG was observed (p =.002), although the 8-OH-dG levels were not significantly different between the patients with cancer and those with polyps. These results suggest an increased level of 8-OH-dG formation in human colorectal tissue with age.

Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Aging; Colon; Colonic Polyps; Colorectal Neoplasms; DNA; Guanine; Humans; Intestinal Polyps; Middle Aged; Oxidative Stress; Rectum

2001