8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Urinary Incontinence, Stress in 2 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the role of spinal serotonergic mechanisms in preventing stress urinary incontinence (SUI) during sneezing, we investigated the effect of intrathecal (it) application of 8-OH-DPAT (a 5-HT(1A) agonist), mCPP (a 5-HT(2B/2C) agonist), and fluoxetine (a serotonin reuptake inhibitor) using a rat model that can examine the neurally evoked continence reflex during sneezing." | 3.75 | Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats. ( Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Kitta, T; Miyazato, M; Sugaya, K; Yoshimura, N, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyazato, M | 1 |
| Kaiho, Y | 1 |
| Kamo, I | 1 |
| Kitta, T | 1 |
| Chancellor, MB | 1 |
| Sugaya, K | 1 |
| Arai, Y | 1 |
| de Groat, WC | 1 |
| Yoshimura, N | 1 |
| Chen, SC | 1 |
| Cheng, CL | 1 |
| Fan, WJ | 1 |
| Chen, JJ | 1 |
| Lai, CH | 1 |
| Peng, CW | 1 |
2 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Piperazines; Pressure; Pyridine | 2009 |
Effect of a 5-HT1A receptor agonist (8-OH-DPAT) on external urethral sphincter activity in a rat model of pudendal nerve injury.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electromyography; Female; Lumbosacral Plexus; Model | 2011 |