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8-hydroxy-2-(di-n-propylamino)tetralin and Tremor

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Tremor in 5 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors."7.85Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017)
"We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors."3.85Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017)
" (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), a 5-HT2 receptor agonist, induced wet-dog shakes, but not hyperthermia and this response was increased 24 h after the chronic administration of CORT."1.30Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats. ( Kitamura, Y; Nagatani, T; Takao, K; Yamawaki, S, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kunisawa, N1
Iha, HA1
Nomura, Y1
Onishi, M1
Matsubara, N1
Shimizu, S1
Ohno, Y1
Kitamura, Y2
Kitagawa, K1
Fujitani, Y1
Shibata, K1
Araki, H1
Sendou, T1
Gomita, Y1
Takao, K1
Nagatani, T1
Yamawaki, S1
Mokler, DJ1
Sullivan, SA1
Winterson, BJ1
Wieland, S1
Kreider, MS1
McGonigle, P1
Lucki, I1

Other Studies

5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Tremor

ArticleYear
Serotonergic modulation of nicotine-induced kinetic tremor in mice.
    Journal of pharmacological sciences, 2017, Volume: 134, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Fenclonine; Humans; Male; Mice; Nicot

2017
The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Body Tem

2007
Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Inflammatory Agents; Behavior, A

1997
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals,

1992
Destruction of the nucleus raphe obscurus and potentiation of serotonin-mediated behaviors following administration of the neurotoxin 3-acetylpyridine.
    Brain research, 1990, Jun-18, Volume: 520, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Brain; Dose-Response R

1990