8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Symptom Cluster in 5 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dextromethorphan, a noncompetitive blocker of the N-methyl-D-aspartate (NMDA) type of glutamate receptor, at 45, 60 and 75 mg/kg, ip doses induced a behavioural syndrome characterised by reciprocal forepaw treading, lateral head-weaving, hind-limb abduction and flat body posture." | 7.73 | Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats. ( Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM, 2005) |
| "Catalepsy was measured in rats using both the cross-legged position test and the bar test." | 5.31 | Repeated treatment with 8-OH-DPAT induces tolerance to its ability to produce the 5-HT1A behavioural syndrome, but not to its ability to attenuate haloperidol-induced catalepsy. ( Colpaert, FC; Kleven, MS; Koek, W; Prinssen, EP, 2000) |
| "Dextromethorphan, a noncompetitive blocker of the N-methyl-D-aspartate (NMDA) type of glutamate receptor, at 45, 60 and 75 mg/kg, ip doses induced a behavioural syndrome characterised by reciprocal forepaw treading, lateral head-weaving, hind-limb abduction and flat body posture." | 3.73 | Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats. ( Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM, 2005) |
| " Dose-response curves created with 8-OH DPAT for the serotonin behavioral syndrome were similar in bile duct-resected and sham-operated rats." | 1.33 | Fatigue of cholestasis and the serotoninergic neurotransmitter system in the rat. ( Bozdayi, AM; Bozkaya, H; Celik, T; Cinar, K; Gören, MZ; Gürdal, H; Onder, FO; Tan, A; Terzioğlu, B; Uzunalimoğlu, O; Yurdaydin, C, 2005) |
| "Catalepsy was measured in rats using both the cross-legged position test and the bar test." | 1.31 | Repeated treatment with 8-OH-DPAT induces tolerance to its ability to produce the 5-HT1A behavioural syndrome, but not to its ability to attenuate haloperidol-induced catalepsy. ( Colpaert, FC; Kleven, MS; Koek, W; Prinssen, EP, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Celik, T | 1 |
| Gören, MZ | 1 |
| Cinar, K | 1 |
| Gürdal, H | 1 |
| Onder, FO | 1 |
| Tan, A | 1 |
| Terzioğlu, B | 1 |
| Bozdayi, AM | 1 |
| Bozkaya, H | 1 |
| Uzunalimoğlu, O | 1 |
| Yurdaydin, C | 1 |
| Gaikwad, RV | 1 |
| Gaonkar, RK | 1 |
| Jadhav, SA | 1 |
| Thorat, VM | 1 |
| Jadhav, JH | 1 |
| Balsara, JJ | 1 |
| Blanchard, RJ | 1 |
| Griebel, G | 1 |
| Guardiola-Lemaître, B | 1 |
| Brush, MM | 1 |
| Lee, J | 1 |
| Blanchard, DC | 1 |
| Prinssen, EP | 1 |
| Koek, W | 1 |
| Colpaert, FC | 1 |
| Kleven, MS | 1 |
| Yamada, J | 1 |
| Sugimoto, Y | 1 |
| Horisaka, K | 1 |
5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Symptom Cluster
| Article | Year |
|---|---|
Fatigue of cholestasis and the serotoninergic neurotransmitter system in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Cholestasis; Dose-Response | 2005 |
Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Behavior, Animal; Buspirone; Ce | 2005 |
An ethopharmacological analysis of selective activation of 5-HT1A receptors: the mouse 5-HT1A syndrome.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Feeding Behavior; Grooming; Male; | 1997 |
Repeated treatment with 8-OH-DPAT induces tolerance to its ability to produce the 5-HT1A behavioural syndrome, but not to its ability to attenuate haloperidol-induced catalepsy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behav | 2000 |
The behavioural effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dopamine Antagonists; Male; Mice; | 1988 |