8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Status Epilepticus in 3 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of 8-OH-DPAT, a 5-HT1A receptor agonist, on electrographic activity during the kainic acid (KA)-induced status epilepticus (SE) was evaluated in male Wistar rats." | 7.74 | Effect of 8-OH-DPAT on electrographic activity during the kainic acid-induced status epilepticus in rats. ( López-Meraz, ML; Martínez, A; Rocha, L, 2007) |
| "The effect of 8-OH-DPAT, a 5-HT1A receptor agonist, on electrographic activity during the kainic acid (KA)-induced status epilepticus (SE) was evaluated in male Wistar rats." | 3.74 | Effect of 8-OH-DPAT on electrographic activity during the kainic acid-induced status epilepticus in rats. ( López-Meraz, ML; Martínez, A; Rocha, L, 2007) |
| "), status epilepticus (SE) of limbic seizures produced by kainic acid (KA, 10 mg/kg, i." | 3.73 | 5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats. ( González-Trujano, ME; Hong, E; López-Meraz, ML; Neri-Bazán, L; Rocha, LL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Guo, Y | 1 |
| Kuang, Y | 1 |
| Wang, S | 2 |
| Jiang, Y | 1 |
| Ding, Y | 1 |
| Ding, M | 1 |
| López-Meraz, ML | 2 |
| González-Trujano, ME | 1 |
| Neri-Bazán, L | 1 |
| Hong, E | 1 |
| Rocha, LL | 1 |
| Martínez, A | 1 |
| Rocha, L | 1 |
3 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Status Epilepticus
| Article | Year |
|---|---|
Serotonin 1A receptor inhibits the status epilepticus induced by lithium-pilocarpine in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analysis of Variance; Animals; Disease Mo | 2014 |
5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Anticonvulsants; Con | 2005 |
Effect of 8-OH-DPAT on electrographic activity during the kainic acid-induced status epilepticus in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Electroencephalography; Excitatory Amino Aci | 2007 |