8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Sexual Dysfunctions, Psychological in 4 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Sexual Dysfunctions, Psychological: Disturbances in sexual desire and the psychophysiologic changes that characterize the sexual response cycle and cause marked distress and interpersonal difficulty. (APA, DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Apomorphine and ± 8-OH-DPAT had an inhibiting effect on sexual behavior, but only females dosed with apomorphine showed a different response in avoiders and approachers, more inhibiting effect in avoiders than approachers." | 1.37 | A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence. ( Chan, JS; de Jong, TR; Olivier, B; Oosting, RS; Snoeren, EM; Waldinger, MD, 2011) |
| " WAY100635 attenuated the effect of fluoxetine; prior treatment with fluoxetine decreased 8-OH-DPAT's potency in reducing lordosis behavior; and progesterone shifted fluoxetine's dose-response curve to the right." | 1.36 | Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition. ( Guptarak, J; Hiegel, C; Sarkar, J; Uphouse, L, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guptarak, J | 1 |
| Sarkar, J | 1 |
| Hiegel, C | 1 |
| Uphouse, L | 1 |
| Ferger, B | 1 |
| Shimasaki, M | 1 |
| Ceci, A | 1 |
| Ittrich, C | 1 |
| Allers, KA | 1 |
| Sommer, B | 1 |
| Snoeren, EM | 1 |
| Chan, JS | 1 |
| de Jong, TR | 1 |
| Waldinger, MD | 1 |
| Olivier, B | 1 |
| Oosting, RS | 1 |
| Seftel, A | 1 |
4 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Sexual Dysfunctions, Psychological
| Article | Year |
|---|---|
Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Female; Fluoxetin | 2010 |
Flibanserin, a drug intended for treatment of hypoactive sexual desire disorder in pre-menopausal women, affects spontaneous motor activity and brain neurochemistry in female rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzimidazoles; Brain Chemistry; Dopamine; Dose-Res | 2010 |
A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Disease Models, Animal; Dopamine Agoni | 2011 |
Re: A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine Agonists; Female; Male; Parox | 2011 |