Page last updated: 2024-10-21

8-hydroxy-2-(di-n-propylamino)tetralin and Retinal Degeneration

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Retinal Degeneration in 1 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research Excerpts

ExcerptRelevanceReference
"BALB/c mice were dosed intraperitoneally with 5, 15, 30, 40, or 50 mg/kg sarpogrelate 48, 24, and 0 hours prior to bright light exposure (10,000 lux) as well as 24 and 48 hours after exposure."1.42Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy. ( Coyner, AS; Datta, S; Gale, MJ; Ku, C; Nicholson, A; Pennesi, ME; Regis, D; Ryals, RC; Sinha, W; Tullis, BE; Wen, Y; Yang, P, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tullis, BE1
Ryals, RC1
Coyner, AS1
Gale, MJ1
Nicholson, A1
Ku, C1
Regis, D1
Sinha, W1
Datta, S1
Wen, Y1
Yang, P1
Pennesi, ME1

Other Studies

1 other study available for 8-hydroxy-2-(di-n-propylamino)tetralin and Retinal Degeneration

ArticleYear
Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Disease Models, Animal; Electroretinography; Inject

2015