Page last updated: 2024-10-21

8-hydroxy-2-(di-n-propylamino)tetralin and Psychomotor Agitation

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Psychomotor Agitation in 3 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"8-OH-DPAT-treated rats showed serotonin syndrome-like behaviors (low body posture, forepaw treading), hyperlocomotion, and decreased body temperature, which were completely inhibited by pretreatment with WAY 100635, a selective 5-HT1A antagonist (n = 8)."5.42A comparison of midazolam and dexmedetomidine for the recovery of serotonin syndrome in rats. ( Eguchi, S; Iwata, H; Kadono, T; Kaminaga, S; Kawano, T; Takahashi, T; Yamanaka, D; Yokoyama, M, 2015)
"8-OH-DPAT-treated rats showed serotonin syndrome-like behaviors (low body posture, forepaw treading), hyperlocomotion, and decreased body temperature, which were completely inhibited by pretreatment with WAY 100635, a selective 5-HT1A antagonist (n = 8)."1.42A comparison of midazolam and dexmedetomidine for the recovery of serotonin syndrome in rats. ( Eguchi, S; Iwata, H; Kadono, T; Kaminaga, S; Kawano, T; Takahashi, T; Yamanaka, D; Yokoyama, M, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawano, T1
Takahashi, T1
Kaminaga, S1
Kadono, T1
Yamanaka, D1
Iwata, H1
Eguchi, S1
Yokoyama, M1
Haleem, DJ1
Gogos, A1
Kwek, P1
van den Buuse, M1

Other Studies

3 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Psychomotor Agitation

ArticleYear
A comparison of midazolam and dexmedetomidine for the recovery of serotonin syndrome in rats.
    Journal of anesthesia, 2015, Volume: 29, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Dexmedetomidine; Hypnotics and Sed

2015
Exaggerated feedback control decreases brain serotonin concentration and elicits hyperactivity in a rat model of diet-restriction-induced anorexia nervosa.
    Appetite, 2009, Volume: 52, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia Nervosa; Brain Chemistry; Feedback, Physio

2009
The role of estrogen and testosterone in female rats in behavioral models of relevance to schizophrenia.
    Psychopharmacology, 2012, Volume: 219, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Estrogens; Female; Ovariectomy

2012