Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin
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8-hydroxy-2-(di-n-propylamino)tetralin and Obesity

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Obesity in 6 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The mifepristone treatment significantly increased plasma corticosterone levels in lean animals, but not in obese animals."1.28Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats. ( Huupponen, R; Koulu, M; Pesonen, U; Rouru, J, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jabeen, B1
Haleem, DJ1
Porter, J1
Van Vrancken, M1
Corll, C1
Thompson, H1
Svec, F1
Lacour, F1
Berger, S1
Espinal, J1
Duhault, J1
Dourish, CT1
Pesonen, U1
Rouru, J1
Huupponen, R1
Koulu, M1
Chaouloff, F1
Jeanrenaud, B1

Reviews

1 review available for 8-hydroxy-2-(di-n-propylamino)tetralin and Obesity

ArticleYear
Multiple serotonin receptors: opportunities for new treatments for obesity?
    Obesity research, 1995, Volume: 3 Suppl 4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite Depressants; Fenfluramine; Humans; Hyperph

1995

Other Studies

5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Obesity

ArticleYear
Desensitization of pre and post synaptic 5-HT-1A receptor responses following long term consumption of sugar rich diet: implications for sugar-induced obesity.
    Pakistan journal of pharmaceutical sciences, 2008, Volume: 21, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Brain; Dietary Sucro

2008
The influence of dehydroepiandrosterone and 8-OH-DPAT on the caloric intake and hypothalamic neurotransmitters of lean and obese Zucker rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dehydroepiandrosterone; Diet; Dose-Response Relatio

2005
8-OH-DPAT induces a selective increase in protein intake in ageing overweight animals.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Diet; Dietary Proteins; Eating; Energy Intak

1994
Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats.
    Brain research. Molecular brain research, 1991, Volume: 10, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arcuate Nucleus of Hypothalamus; Corticosterone; Ge

1991
Hyperinsulinemia of the genetically obese (fa/fa) rat is decreased by a low dose of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Eating; Glucose; Insulin; Male; Naph

1988