8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Neuralgia in 4 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 7.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 3.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Munawar, N | 1 |
| Bitar, MS | 1 |
| Masocha, W | 1 |
| Sagalajev, B | 2 |
| Bourbia, N | 1 |
| Beloushko, E | 1 |
| Wei, H | 2 |
| Pertovaara, A | 2 |
| Hu, B | 1 |
| Doods, H | 1 |
| Treede, RD | 1 |
| Ceci, A | 1 |
| Viisanen, H | 1 |
4 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Neuralgia
| Article | Year |
|---|---|
Activation of 5-HT1A Receptors Normalizes the Overexpression of Presynaptic 5-HT1A Receptors and Alleviates Diabetic Neuropathic Pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2023 |
Bidirectional amygdaloid control of neuropathic hypersensitivity mediated by descending serotonergic pathways acting on spinal 5-HT3 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Dizocilpine Maleate; Glutamic Acid; Male; | 2015 |
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agen | 2016 |
Descending antinociception induced by secondary somatosensory cortex stimulation in experimental neuropathy: role of the medullospinal serotonergic pathway.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Disease Models, Animal; Electric | 2017 |