Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin
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8-hydroxy-2-(di-n-propylamino)tetralin and Muscle Relaxation

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Muscle Relaxation in 5 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" 3 The additional smooth muscle contraction stimulated by 5-HT was increased in the presence of the competitive substrate inhibitor for nitric oxide synthase, NG-nitro-L-arginine methyl ester (L-NAME, 100 microM)."3.68Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery. ( Clark, AH; Garland, CJ; Seager, JM, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buchheit, KH1
Buhl, T1
Carter, D1
Champney, M1
Hwang, B1
Eglen, RM1
Fujiwara, T1
Chiba, S1
Seager, JM1
Clark, AH1
Garland, CJ1
Murakami, H1
Sano, M1
Tsukimura, T1
Yamazaki, A1

Other Studies

5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Muscle Relaxation

ArticleYear
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding

1994
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter

1995
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models,

1995
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
    British journal of pharmacology, 1992, Volume: 105, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Fe

1992
The relaxation induced by indole and nonindole 5-HT agonists in the molluscan smooth muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 90, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bivalvia; Cyclic AMP; In Vitro Techniques; Indoles;

1988