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8-hydroxy-2-(di-n-propylamino)tetralin and Muscle Contraction

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Muscle Contraction in 53 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" in doses that produce apnea."7.70Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000)
" in doses that produce apnea."3.70Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000)
" 3 The additional smooth muscle contraction stimulated by 5-HT was increased in the presence of the competitive substrate inhibitor for nitric oxide synthase, NG-nitro-L-arginine methyl ester (L-NAME, 100 microM)."3.68Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery. ( Clark, AH; Garland, CJ; Seager, JM, 1992)
" Intrathecal injection of 5-methoxy-N,N'-dimethyltryptamine (5-MeODMT), (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) or 2,5-dimethoxy-alpha,4-dimethylbenzene ethamine hydrochloride (DOM) produced dose-related back muscle contractions (BMC) and wet dog shakes (WDS) which were both markedly attenuated by intraperitoneal pretreatment with either ritanserin (1 mg kg-1), ketanserin (0."3.68Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats. ( Fone, KC; Marsden, CA; Robinson, AJ, 1991)
"Pretreatment with ketanserin (10 microM), a 5-HT2 antagonist, tropisetron (1 microM), a 5-HT3/4 antagonist, SDZ 216-525 (1 to 10 microM) and pindobind (10 microM), both selective 5-HT1A antagonists, or capsaicin (10 microM), which depletes sensory nerves from neuropeptides, had no effect on the inhibition of the cholinergic contraction by 8-OH-DPAT (10 to 30 microM)."1.30The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro. ( De Leyn, P; Demedts, MG; Deneffe, G; Dupont, LJ; Pype, JL; Verleden, GM, 1998)
"5."1.28Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery. ( Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D, 1991)
" In a solution containing 20 mM K+ 5-HT induced a biphasic dose-response curve (DRC) in intact arteries."1.28Serotonergic responses in rabbit ophthalmic artery: a pharmacological characterization. ( Uusitalo, H; van Breemen, C; Zschauer, A, 1991)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.55)18.7374
1990's30 (56.60)18.2507
2000's14 (26.42)29.6817
2010's4 (7.55)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Cannon, JG1
Raghupathi, R1
Moe, ST1
Johnson, AK1
Long, JP1
Wainscott, DB1
Cohen, ML3
Schenck, KW2
Audia, JE1
Nissen, JS1
Baez, M1
Kursar, JD1
Lucaites, VL1
Nelson, DL1
Barlocco, D3
Cignarella, G3
Montesano, F3
Leonardi, A4
Mella, M1
Toma, L1
Bolognesi, ML1
Budriesi, R1
Cavalli, A1
Chiarini, A1
Gotti, R1
Minarini, A1
Poggesi, E3
Recanatini, M1
Rosini, M1
Tumiatti, V1
Melchiorre, C1
Mensonides-Harsema, MM1
Liao, Y1
Böttcher, H1
Bartoszyk, GD1
Greiner, HE1
Harting, J1
de Boer, P1
Wikström, HV1
Piaz, VD1
Giovannoni, MP1
De Benedetti, PG2
Fanelli, F2
Perrone, R3
Berardi, F3
Colabufo, NA3
Lacivita, E3
Leopoldo, M3
Tortorella, V2
Motta, G1
Testa, R1
Seeber, M1
Contino, M2
Niso, M1
Leirão, IP1
Zoccal, DB1
Gargaglioni, LH1
da Silva, GSF1
Chiba, H1
Mitsui, T1
Kitta, T1
Ohmura, Y1
Moriya, K1
Kanno, Y1
Yoshioka, M1
Shinohara, N1
Cheng, CL3
de Groat, WC2
Chen, SC1
Fan, WJ1
Chen, JJ2
Lai, CH1
Peng, CW1
Chang, HH1
Havton, LA1
Thor, KB1
Katofiasc, MA1
Danuser, H1
Springer, J1
Schaus, JM1
Lograno, MD1
Romano, MR1
McLean, DL1
Sillar, KT1
Moffatt, JD1
Cocks, TM1
Page, CP1
Delgado, M1
Caicoya, AG1
Greciano, V1
Benhamú, B1
López-Rodríguez, ML1
Fernández-Alfonso, MS1
Pozo, MA1
Manzanares, J1
Fuentes, JA1
Clément, P1
Bernabé, J1
Kia, HK1
Alexandre, L1
Giuliano, F1
Chang, HY1
Nóbrega, AC1
Meintjes, AF1
Ally, A3
Wilson, LB1
Miranda, FJ1
Torregrosa, G1
Salom, JB1
Alabadí, JA1
Jover, T1
Barberá, MD1
Alborch, E1
Ram, JL2
Judge, K1
Jednak, MA1
Miyamoto, A1
Sakota, T1
Nishio, A1
Buchheit, KH1
Buhl, T1
Shimamoto, Y1
Shimamoto, H1
Kwan, CY1
Daniel, EE1
Hong, E1
Castillo, C1
Ibarra, M1
Villalobos, R1
Carter, D1
Champney, M1
Hwang, B1
Eglen, RM1
Fujiwara, T1
Chiba, S1
Soslau, G1
Silverberg, M1
Brodsky, I1
McCarty, PP1
Caringi, D2
Koester, DM1
Kobayashi, T2
Mokler, DJ2
Asmundsson, G1
Ishide, T1
Teng, GQ1
Williams, J1
Zhang, L1
Purdy, R1
Pearce, WJ1
Dupont, LJ1
Pype, JL1
Demedts, MG1
De Leyn, P1
Deneffe, G1
Verleden, GM1
Darmani, NA1
Ahmad, B1
O'Gara, BA1
Illuzzi, FA1
Chung, M1
Portnoy, AD1
Fraga, K1
Frieman, VB1
Hemrick-Luecke, SH1
Sahibzada, N1
Ferreira, M1
Wasserman, AM1
Taveira-DaSilva, AM1
Gillis, RA1
Galligan, JJ1
Seager, JM1
Clark, AH1
Garland, CJ1
Foy, RA1
Myles, JL1
Wilkerson, RD1
Parsons, AA1
Motevalian, M1
Whalley, ET1
Tadipatri, S1
van Heuven-Nolsen, D1
Feniuk, W2
Saxena, PR1
Fone, KC1
Robinson, AJ1
Marsden, CA2
Zschauer, A1
van Breemen, C1
Uusitalo, H1
Wright, IK1
Ismail, H1
Upton, N1
Perren, MJ1
Humphrey, PP1
Murakami, H1
Sano, M1
Tsukimura, T1
Yamazaki, A1
Kreiman, MA1
Gole, D1
Paiva, MQ1
Caramona, MM1
Osswald, W1

Other Studies

53 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Muscle Contraction

ArticleYear
Preparation and pharmacological evaluation of enantiomers of certain nonoxygenated aporphines: (+)- and (-)-aporphine and (+)- and (-)-10-methylaporphine.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Animals; Aporphines; Dopamine Agents; Guinea Pigs; Hemodynamics; Muscle Contraction; Muscle, Smooth;

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate;

1993
Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton.
    Journal of medicinal chemistry, 1999, Jan-14, Volume: 42, Issue:1

    Topics: Adrenergic Antagonists; Animals; Aorta, Thoracic; CHO Cells; Cricetinae; Humans; In Vitro Techniques

1999
WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; CHO Cells; Clonin

1999
Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
    Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Frontal Lobe; Guinea Pigs; Hypother

2000
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; CHO Cells; Cricetinae; HeLa Cells; Humans; In Vitro Te

2001
Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
    Journal of medicinal chemistry, 2003, Feb-13, Volume: 46, Issue:4

    Topics: Animals; Brain; Cell Line; Cricetinae; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Isoxazoles;

2003
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha 1d adrenergic receptor.
    Journal of medicinal chemistry, 2004, Apr-08, Volume: 47, Issue:8

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals;

2004
Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Journal of medicinal chemistry, 2004, Dec-16, Volume: 47, Issue:26

    Topics: Amides; Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Muscle Contraction; Muscle

2004
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pi

2007
Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats.
    Pflugers Archiv : European journal of physiology, 2020, Volume: 472, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Abdominal Muscles; Animals; Diaphragm; Exhalation; GABA-A Re

2020
The role of serotonergic mechanism in the rat prefrontal cortex for controlling the micturition reflex: An in vivo microdialysis study.
    Neurourology and urodynamics, 2016, Volume: 35, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Dopamine; Female; Glutamic Acid; Microd

2016
Role of 5-HT1A receptors in control of lower urinary tract function in anesthetized rats.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia, General; Animals; Electromyography; Female; Musc

2010
Effect of a 5-HT1A receptor agonist (8-OH-DPAT) on external urethral sphincter activity in a rat model of pudendal nerve injury.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electromyography; Female; Lumbosacral Plexus; Model

2011
Serotonergic 5-HT(1A) receptor agonist (8-OH-DPAT) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury.
    Experimental neurology, 2013, Volume: 239

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electromyography; Female; Injections, Intravenous;

2013
The role of 5-HT(1A) receptors in control of lower urinary tract function in cats.
    Brain research, 2002, Aug-16, Volume: 946, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetic Acid; Animals; Cats; Cystitis; Dose-Response Relation

2002
Pharmacological characterization of the 5-HT1A, 5-HT2 and 5-HT3 receptors in the bovine ciliary muscle.
    European journal of pharmacology, 2003, Mar-07, Volume: 464, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cattle; Cell Membrane; Ciliar

2003
Divergent actions of serotonin receptor activation during fictive swimming in frog embryos.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2004, Volume: 190, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Axons; Central Nervous System; C

2004
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
    British journal of pharmacology, 2004, Volume: 141, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum

2004
Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors.
    European journal of pharmacology, 2005, Mar-21, Volume: 511, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors;

2005
D2-like receptors mediate the expulsion phase of ejaculation elicited by 8-hydroxy-2-(di-N-propylamino)tetralin in rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Ejaculation; Inje

2006
Serotonergic drugs and spinal cord transections indicate that different spinal circuits are involved in external urethral sphincter activity in rats.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Electromyography; Female; Hyd

2007
Modulation of reflex pressor response to contraction and effect on substance P release by spinal 5-HT1A receptors.
    The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Female; Male; Microdialysis;

1995
Characterization of 5-hydroxytryptamine receptors in goat cerebral arteries.
    General pharmacology, 1995, Volume: 26, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Arteries; Dose-Response Relationship, Drug

1995
Antagonists of cholinergic and serotonergic responses of Aplysia buccal muscle.
    Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology, 1994, Volume: 107, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; Atropine; Cholinergic Antag

1994
Characterization of 5-hydroxytryptamine receptors on the isolated pig basilar artery by functional and radioligand binding studies.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basilar Artery; Binding, Competitive; Dose-Response

1994
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding

1994
Rauwolscine induces contraction in the dog mesenteric artery precontracted with KCl and endothelin-1: mediation via 5-hydroxytryptamine1-like receptors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Dogs; Drug Interactio

1993
Characterization of the alpha-adrenergic effect of some 5-HT1A agonists.
    Proceedings of the Western Pharmacology Society, 1993, Volume: 36

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aorta, Thoracic; Buspirone; In Vitro Techniques; Mu

1993
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter

1995
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models,

1995
ATP modification of serotonin-induced contraction of the rat pulmonary artery.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 214, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine Triphosphate; Animals; Cyclic AMP; Male; Muscle Co

1997
Central 5-HT1A modulation of cardiovascular responses to tibial nerve stimulation-evoked muscle contraction.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Glutamic Acid; Heart Rate; Male; Me

1997
Extracellular serotonin changes in VLM during muscle contraction: effects of 5-HT1A-receptor activation.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Electric Stimulation; Heart Rate; K

1997
Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Carotid Artery, Common; Cerebral Arteries; F

1998
The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Capsai

1998
Long-term sequential determination of behavioral ontogeny of 5-HT1A and 5-HT2 receptor functions in the rat.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Body Temperature; Female; Head Moveme

1999
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
    General pharmacology, 1999, Volume: 32, Issue:6

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Re

1999
5-Hydroxytryptamine(1A) receptor activation enhances norepinephrine release from nerves in the rabbit saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Elect

1999
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug I

2000
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by 5-hydroxytryptamine1A receptor agonists in guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bethanechol; Bethanechol Compounds; Choline; Electr

1992
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
    British journal of pharmacology, 1992, Volume: 105, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Fe

1992
Characterization of 5-hydroxytryptamine receptors in bovine coronary arteries.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cattle; Dose-Response Relationship, Drug; Endotheli

1992
Contractile effects of 8-hydroxy-2-(di-n-propylamino)tetralin and flesinoxan in human isolated basilar artery.
    European journal of pharmacology, 1991, Sep-04, Volume: 202, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Antihypertensive Agents; Basilar Artery; Humans; In Vitro Te

1991
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)te

1991
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, S

1991
Serotonergic responses in rabbit ophthalmic artery: a pharmacological characterization.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Dr

1991
Effect of isolation rearing on 5-HT agonist-induced responses in the rat.
    Psychopharmacology, 1991, Volume: 105, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Male; Methoxydimeth

1991
Canine, but not rat bladder contracts to serotonin via activation of 5HT2 receptors.
    The Journal of urology, 1990, Volume: 143, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dogs; Dose-Response Relationship, Drug; Ergolines;

1990
Vascular actions of 8-OH-DPAT mediated via activation of non-5-HT1A receptors.
    British journal of pharmacology, 1989, Volume: 98 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Con

1989
The relaxation induced by indole and nonindole 5-HT agonists in the molluscan smooth muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 90, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bivalvia; Cyclic AMP; In Vitro Techniques; Indoles;

1988
LY165163 and 8-OH-DPAT have agonist effects on a serotonin responsive muscle of Aplysia.
    European journal of pharmacology, 1987, Jul-09, Volume: 139, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; In Vitro Techniques; Ketans

1987
The actions of 5-hydroxytryptamine receptor agonists and antagonists at pre- and postjunctional level on the canine saphenous vein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dogs; In Vitro Techniques; Muscle Contraction; Musc

1988