8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Morphine Dependence in 3 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In summary, we conclude that morphine addiction is associated with supersensitivity of 5-HT1A serotonin receptors and alpha2-adrenoceptors (autoreceptors and heteroreceptors) that modulate the synthesis of monoamines in brain." | 1.31 | Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats. ( Esteban, S; García-Sevilla, JA; Sastre-Coll, A, 2002) |
| " Morphine produces a plethora of pharmacological effects and its chronic administration induces several side-effects." | 1.29 | Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment. ( Cox, BM; Noble, F, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noble, F | 1 |
| Cox, BM | 1 |
| Sastre-Coll, A | 1 |
| Esteban, S | 1 |
| García-Sevilla, JA | 1 |
| Berthold, H | 1 |
| Fozard, JR | 1 |
| Engel, G | 1 |
3 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Morphine Dependence
| Article | Year |
|---|---|
Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Aminobutyrates; Analgesics; Animals; Brai | 1996 |
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoam | 2002 |
5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Ani | 1989 |