8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Memory Disorders in 9 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Rats were acutely dosed with vortioxetine, ondansetron (5-HT3 receptor antagonist) or flesinoxan (5-HT1A receptor agonist)." | 1.40 | Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 receptor antagonism. ( du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C, 2014) |
| "Working memory deficits were elicited by 8-OH-DPAT without affecting reference memory." | 1.31 | Effects of histidine on working memory deficits induced by the 5-HT1A-receptor agonist 8-OH-DPAT. ( Isayama, S; Kamei, C; Nishiga, M; Sugimoto, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanku, RKK | 1 |
| John, JS | 1 |
| Salkovitz, M | 1 |
| Ilies, MA | 1 |
| Walker, EA | 1 |
| du Jardin, KG | 1 |
| Jensen, JB | 1 |
| Sanchez, C | 1 |
| Pehrson, AL | 1 |
| Bert, B | 1 |
| Voigt, JP | 1 |
| Kusserow, H | 1 |
| Theuring, F | 1 |
| Rex, A | 1 |
| Fink, H | 1 |
| Egashira, N | 1 |
| Yano, A | 1 |
| Ishigami, N | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Fujioka, M | 1 |
| Matsushita, M | 1 |
| Nishimura, R | 1 |
| Fujiwara, M | 1 |
| Lu, MC | 1 |
| Hsieh, MT | 1 |
| Wu, CR | 1 |
| Cheng, HY | 1 |
| Hsieh, CC | 1 |
| Lin, YT | 1 |
| Peng, WH | 1 |
| Ohno, M | 1 |
| Yamamoto, T | 1 |
| Watanabe, S | 1 |
| Buhot, MC | 1 |
| Patra, SK | 1 |
| Naïli, S | 1 |
| Pache, DM | 1 |
| Sewell, RD | 1 |
| Spencer, PS | 1 |
| Isayama, S | 1 |
| Sugimoto, Y | 1 |
| Nishiga, M | 1 |
| Kamei, C | 1 |
9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Memory Disorders
| Article | Year |
|---|---|
Potential learning and memory disruptors and enhancers in a simple, 1-day operant task in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adjuvants, Anesthesia; Animals; Conditioning, Operant; Disea | 2018 |
Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 receptor antagonism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Disease Models, Animal; Dose-Response R | 2014 |
Increasing the number of 5-HT(1A)-receptors in cortex and hippocampus does not induce mnemonic deficits in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Cerebral Cortex; Cues; Hippocam | 2009 |
Investigation of mechanisms mediating 8-OH-DPAT-induced impairment of spatial memory: involvement of 5-HT1A receptors in the dorsal hippocampus in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; | 2006 |
Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Baclofen; Bicuculline; Cycloh | 2007 |
Working memory deficits induced by intrahippocampal administration of 8-OH-DPAT, a 5-HT1A receptor agonist, in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hippocampus; Male; Memory Disorders; Memory, Short- | 1993 |
Spatial memory deficits following stimulation of hippocampal 5-HT1B receptors in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Handling, Psychological; Hippocam | 1995 |
Detecting drug effects on short-term memory function using a combined delayed matching and non-matching to position task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Conditioning, Operant; Dose-Respo | 1999 |
Effects of histidine on working memory deficits induced by the 5-HT1A-receptor agonist 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; | 2001 |