8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Inadequate Sleep in 9 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
| Excerpt | Relevance | Reference |
|---|---|---|
| "In animals, sleep deprivation and pharmacologic treatment with antidepressants exert similar effects on 5-HT neurotransmission, notably functional desensitization of 5-HT1A autoreceptors located on 5-HT neurons in the dorsal raphe nucleus (DRN)." | 1.33 | Glucocorticoid receptor-dependent desensitization of 5-HT1A autoreceptors by sleep deprivation: studies in GR-i transgenic mice. ( Adrien, J; Barden, N; Evrard, A; Hamon, M, 2006) |
| "Significantly, sleep deprivation-induced phase-advance shifts potentiated by brief LL (approximately 9 h) at ZT 0 were blocked by pindolol, suggesting that these behavioral shifts could be mediated by the same SCN 5-HT1A receptor phase-resetting pathway as that activated by 8-OH-DPAT treatment." | 1.33 | Serotonergic mediation of constant light-potentiated nonphotic phase shifting of the circadian locomotor activity rhythm in Syrian hamsters. ( Duncan, MJ; Glass, JD; Knoch, ME; Siegel, D, 2006) |
| "Total sleep deprivation (TSD) for one or more nights produces a rapid antidepressant response in humans." | 1.30 | Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat. ( Fornal, CA; Gardner, JP; Jacobs, BL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 8 (88.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, H | 1 |
| Ma, A | 1 |
| Wang, YX | 1 |
| Pertovaara, A | 1 |
| Fedorkova, L | 1 |
| Rutishauser, U | 1 |
| Prosser, R | 1 |
| Shen, H | 1 |
| Glass, JD | 3 |
| Harvey, MT | 1 |
| Smith, RL | 1 |
| May, ME | 1 |
| Caruso, M | 1 |
| Roberts, C | 1 |
| Patterson, TG | 1 |
| Valdovinos, M | 1 |
| Kennedy, CH | 1 |
| Knoch, ME | 2 |
| Gobes, SM | 1 |
| Pavlovska, I | 1 |
| Su, C | 1 |
| Mistlberger, RE | 1 |
| Roman, V | 1 |
| Walstra, I | 1 |
| Luiten, PG | 1 |
| Meerlo, P | 1 |
| Evrard, A | 1 |
| Barden, N | 1 |
| Hamon, M | 2 |
| Adrien, J | 2 |
| Siegel, D | 1 |
| Duncan, MJ | 1 |
| Gardner, JP | 1 |
| Fornal, CA | 1 |
| Jacobs, BL | 1 |
| Boutrel, B | 1 |
| Monaca, C | 1 |
| Hen, R | 1 |
9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Inadequate Sleep
| Article | Year |
|---|---|
Role of spinal 5-HT receptors in cutaneous hypersensitivity induced by REM sleep deprivation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Injections, Spinal; Male; Microinjections; Pain; Pa | 2008 |
Removal of polysialic acid from the SCN potentiates nonphotic circadian phase resetting.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Blotting, Western; Circadian Rhythm; Crice | 2002 |
Possible role for the 5-HT1A receptor in the behavioral effects of REM sleep deprivation on free-operant avoidance responding in rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Conditioning, Operant; Dose-Res | 2004 |
Short-term exposure to constant light promotes strong circadian phase-resetting responses to nonphotic stimuli in Syrian hamsters.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Biological | 2004 |
Too little sleep gradually desensitizes the serotonin 1A receptor system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Chronic Disease; Depression; Dise | 2005 |
Glucocorticoid receptor-dependent desensitization of 5-HT1A autoreceptors by sleep deprivation: studies in GR-i transgenic mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Autoreceptors; Dose-Response | 2006 |
Serotonergic mediation of constant light-potentiated nonphotic phase shifting of the circadian locomotor activity rhythm in Syrian hamsters.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Light; Male; Mesocric | 2006 |
Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Cats; Male; Neurons; Raphe Nucle | 1997 |
Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HT1A knock-out mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Animals; Arousal; Circadian Rhyth | 2002 |