8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Hyperphagia in 22 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Hyperphagia: Ingestion of a greater than optimal quantity of food.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Daily corticosterone treatment decreased body weight and food intake." | 1.28 | Repeated corticosterone treatment attenuates behavioural and neuroendocrine responses to 8-hydroxy-2-(di-n-propylamino) tetralin in rats. ( Haleem, DJ, 1992) |
| "However, hyperphagia was most evident in diestrous females and least evident in proestrous and estrous rats." | 1.28 | Gender and estrous cycle differences in the response to the 5-HT1A agonist 8-OH-DPAT. ( Caldarola-Pastuszka, M; Salamanca, S; Uphouse, L, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 8 (36.36) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brosda, J | 1 |
| Müller, N | 1 |
| Bert, B | 1 |
| Fink, H | 1 |
| Jabeen, B | 2 |
| Haleem, DJ | 5 |
| Inam, QU | 3 |
| Haleem, MA | 3 |
| Scopinho, AA | 1 |
| Guimarães, FS | 1 |
| Corrêa, FM | 1 |
| Resstel, LB | 1 |
| Miryala, CS | 1 |
| Maswood, N | 1 |
| Uphouse, L | 2 |
| Ebenezer, IS | 1 |
| Surujbally, A | 1 |
| Hartley, JE | 1 |
| Fletcher, A | 1 |
| Dourish, CT | 5 |
| Francis, J | 1 |
| Cooper, SJ | 1 |
| Yamada, J | 4 |
| Sugimoto, Y | 4 |
| Yoshikawa, T | 3 |
| Horisaka, K | 1 |
| Kunitomo, M | 1 |
| Kaur, G | 1 |
| Kulkarni, SK | 1 |
| Salamanca, S | 1 |
| Caldarola-Pastuszka, M | 1 |
| Hutson, PH | 2 |
| Curzon, G | 2 |
| Chaouloff, F | 1 |
| Serrurrier, B | 1 |
| Mérino, D | 1 |
| Laude, D | 1 |
| Elghozi, JL | 1 |
| Gilbert, F | 1 |
1 review available for 8-hydroxy-2-(di-n-propylamino)tetralin and Hyperphagia
| Article | Year |
|---|---|
Multiple serotonin receptors: opportunities for new treatments for obesity?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite Depressants; Fenfluramine; Humans; Hyperph | 1995 |
21 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Hyperphagia
| Article | Year |
|---|---|
Modulatory Role of Postsynaptic 5-Hydroxytryptamine Type 1A Receptors in (±)-8-Hydroxy-N,N-dipropyl-2-aminotetralin-Induced Hyperphagia in Mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Disease Models, Animal; Dose-Response Relati | 2015 |
Desensitization of pre and post synaptic 5-HT-1A receptor responses following long term consumption of sugar rich diet: implications for sugar-induced obesity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Brain; Dietary Sucro | 2008 |
Long-term consumption of sugar-rich diet decreases the effectiveness of somatodendritic serotonin-1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dietary Sucrose; Eating; Feedback, Physiological; H | 2008 |
Attenuation of somatodendritic responses to 8-hydroxy-2-di-npropylamino tetralin following long-term dietary sugar consumption in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite Regulation; Brain; Dietary Sucrose; Hyperp | 2009 |
Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzoxazines; Cannabidiol; Drug Interactions; Eatin | 2011 |
Fluoxetine prevents 8-OH-DPAT-induced hyperphagia in Fischer inbred rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Eating; Estradiol; Female; Fluoxetine; Hy | 2011 |
Effects of long term consumption of sugar as part of meal on serotonin 1-a receptor dependent responses.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Brain; Dietary Sucrose; Eatin | 2006 |
The effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) on food intake in non-deprived C57BL6 mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Eating; Hyperphag | 2007 |
The effects of WAY-100135 and 8-hydroxy-2-(di-n-propylamino)tetralin on feeding in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; | 1994 |
Lack of interaction between devazepide and 8-OH-DPAT-induced hyperphagia in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepinones; Devazepide; Drug Interactions; E | 1996 |
Effects of a nitric oxide synthase inhibitor on 5-HT1A receptor agonist 8-OH-DPAT-induced hyperphagia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Eating; Enzyme Inhibitors; Hyperphagia; Male; NG-Ni | 1996 |
Effects of adrenalectomy on hyperphagia induced by the 5-HT1A receptor agonist 8-OH-DPAT and 2-deoxy-D-glucose in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Analysis of | 1998 |
Involvement of nitric oxide in the 5-HT1A autoreceptor-mediated hyperphagia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Enzyme Inhibitors; Hyperphagia; Indazoles; Male; NG | 1999 |
A nitric oxide synthase inhibitor reduces hyperphagia induced in rats by the 5-HT(1A) receptor agonist, 8-OH-DPAT, independently of hypothalamic serotonin metabolism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Hyperp | 2000 |
Investigations on possible serotonergic involvement in effects of OB-200G (polyherbal preparation) on food intake in female mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Disease Models, Animal; Energy Intake; Feeding Beha | 2001 |
Repeated corticosterone treatment attenuates behavioural and neuroendocrine responses to 8-hydroxy-2-(di-n-propylamino) tetralin in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Body Weight; Brain; Corticosteron | 1992 |
Gender and estrous cycle differences in the response to the 5-HT1A agonist 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Estrus; Feeding Behavior; Female; | 1991 |
Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Eating; Feeding and Eating Disorders; Hydrox | 1986 |
Feeding responses to a high dose of 8-OH-DPAT in young and adult rats: influence of food texture.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animal Feed; Animals; Blood Glucose; Feeding Behavior | 1988 |
Effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Eating; Hyperphagia | 1987 |
Evidence that the hyperphagic response to 8-OH-DPAT is mediated by 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catecholamines; Drug Interactions; Feeding and Eati | 1988 |