8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Glioma in 5 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin (5-HT) induced a transient rise of the cyclic GMP level in neuroblastoma X glioma hybrid cells, half-maximally at 1 microM 5-HT." | 3.67 | Serotonin raises the cyclic GMP level in a neuronal cell line via 5-HT3 receptors. ( Hamprecht, B; Reiser, G, 1989) |
| "Alniditan is a new migraine-abortive agent." | 1.29 | Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin ( Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leysen, JE | 1 |
| Gommeren, W | 1 |
| Heylen, L | 1 |
| Luyten, WH | 1 |
| Van de Weyer, I | 1 |
| Vanhoenacker, P | 1 |
| Haegeman, G | 1 |
| Schotte, A | 1 |
| Van Gompel, P | 1 |
| Wouters, R | 1 |
| Lesage, AS | 1 |
| Cappelli, A | 1 |
| Anzini, M | 1 |
| Vomero, S | 1 |
| Mennuni, L | 1 |
| Makovec, F | 1 |
| Doucet, E | 1 |
| Hamon, M | 1 |
| Bruni, G | 1 |
| Romeo, MR | 1 |
| Menziani, MC | 1 |
| De Benedetti, PG | 1 |
| Langer, T | 1 |
| Banerjee, P | 1 |
| Berry-Kravis, E | 1 |
| Bonafede-Chhabra, D | 1 |
| Dawson, G | 1 |
| Saitoh, K | 1 |
| Mikuni, M | 1 |
| Ikeda, M | 1 |
| Yamazaki, C | 1 |
| Tomita, U | 1 |
| Takahashi, K | 1 |
| Reiser, G | 1 |
| Hamprecht, B | 1 |
5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Glioma
| Article | Year |
|---|---|
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorde | 1996 |
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
Topics: Animals; Benzene; Binding Sites; Glioma; Guanidine; Mice; Models, Molecular; Molecular Structure; Ne | 1998 |
Heterologous expression of the serotonin 5-HT1A receptor in neural and non-neural cell lines.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Cell Line; CHO Cells; Cricetinae | 1993 |
Serotonin-induced 5-HT1A receptor desensitization in C6BU-1 glioma cells transfected with 5-HT1A receptor gene.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Neoplasms; Colforsin; Cyclic AMP; Dose-Respon | 1995 |
Serotonin raises the cyclic GMP level in a neuronal cell line via 5-HT3 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Line; Cyclic AMP; Cyclic GMP; Glioma; Mice; Ne | 1989 |