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8-hydroxy-2-(di-n-propylamino)tetralin and Glial Cell Tumors

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Glial Cell Tumors in 5 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Research Excerpts

ExcerptRelevanceReference
"Serotonin (5-HT) induced a transient rise of the cyclic GMP level in neuroblastoma X glioma hybrid cells, half-maximally at 1 microM 5-HT."3.67Serotonin raises the cyclic GMP level in a neuronal cell line via 5-HT3 receptors. ( Hamprecht, B; Reiser, G, 1989)
"Alniditan is a new migraine-abortive agent."1.29Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin ( Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leysen, JE1
Gommeren, W1
Heylen, L1
Luyten, WH1
Van de Weyer, I1
Vanhoenacker, P1
Haegeman, G1
Schotte, A1
Van Gompel, P1
Wouters, R1
Lesage, AS1
Cappelli, A1
Anzini, M1
Vomero, S1
Mennuni, L1
Makovec, F1
Doucet, E1
Hamon, M1
Bruni, G1
Romeo, MR1
Menziani, MC1
De Benedetti, PG1
Langer, T1
Banerjee, P1
Berry-Kravis, E1
Bonafede-Chhabra, D1
Dawson, G1
Saitoh, K1
Mikuni, M1
Ikeda, M1
Yamazaki, C1
Tomita, U1
Takahashi, K1
Reiser, G1
Hamprecht, B1

Other Studies

5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Glial Cell Tumors

ArticleYear
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorde

1996
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
    Journal of medicinal chemistry, 1998, Feb-26, Volume: 41, Issue:5

    Topics: Animals; Benzene; Binding Sites; Glioma; Guanidine; Mice; Models, Molecular; Molecular Structure; Ne

1998
Heterologous expression of the serotonin 5-HT1A receptor in neural and non-neural cell lines.
    Biochemical and biophysical research communications, 1993, Apr-15, Volume: 192, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Cell Line; CHO Cells; Cricetinae

1993
Serotonin-induced 5-HT1A receptor desensitization in C6BU-1 glioma cells transfected with 5-HT1A receptor gene.
    Neuroscience letters, 1995, Oct-27, Volume: 199, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Neoplasms; Colforsin; Cyclic AMP; Dose-Respon

1995
Serotonin raises the cyclic GMP level in a neuronal cell line via 5-HT3 receptors.
    European journal of pharmacology, 1989, May-11, Volume: 172, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Line; Cyclic AMP; Cyclic GMP; Glioma; Mice; Ne

1989