8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Epilepsy, Complex Partial in 2 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Epilepsy, Complex Partial: A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "), status epilepticus (SE) of limbic seizures produced by kainic acid (KA, 10 mg/kg, i." | 3.73 | 5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats. ( González-Trujano, ME; Hong, E; López-Meraz, ML; Neri-Bazán, L; Rocha, LL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López-Meraz, ML | 1 |
| González-Trujano, ME | 1 |
| Neri-Bazán, L | 1 |
| Hong, E | 1 |
| Rocha, LL | 1 |
| Watanabe, K | 1 |
| Minabe, Y | 1 |
| Ashby, CR | 1 |
| Katsumori, H | 1 |
2 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Epilepsy, Complex Partial
| Article | Year |
|---|---|
5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Anticonvulsants; Con | 2005 |
Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Electric Stimulatio | 1998 |