8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Epilepsy, Absence in 3 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jakus, R | 1 |
| Graf, M | 1 |
| Ando, RD | 1 |
| Balogh, B | 1 |
| Gacsalyi, I | 1 |
| Levay, G | 1 |
| Kantor, S | 1 |
| Bagdy, G | 3 |
| Gerber, K | 2 |
| Filakovszky, J | 2 |
| Halasz, P | 1 |
3 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Epilepsy, Absence
| Article | Year |
|---|---|
Effect of two noncompetitive AMPA receptor antagonists GYKI 52466 and GYKI 53405 on vigilance, behavior and spike-wave discharges in a genetic rat model of absence epilepsy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Behavior, Animal; Benzodiazepines; Dose-Re | 2004 |
The 5-HT1A agonist 8-OH-DPAT increases the number of spike-wave discharges in a genetic rat model of absence epilepsy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Disease Models, Animal; Dose-Res | 1998 |
A serotonin-1A receptor agonist and an N-methyl-D-aspartate receptor antagonist oppose each others effects in a genetic rat epilepsy model.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Brain Chemistry; Disease Models, | 1999 |