8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Brain Injuries in 8 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, B | 1 |
| Song, Z | 1 |
| Liang, G | 1 |
| Lei, W | 1 |
| Wang, Z | 1 |
| Liu, E | 1 |
| Li, X | 1 |
| Liu, H | 1 |
| Cheng, JP | 4 |
| Hoffman, AN | 2 |
| Zafonte, RD | 5 |
| Kline, AE | 7 |
| McAloon, RL | 1 |
| Henderson, KA | 1 |
| Bansal, UK | 1 |
| Ganti, BM | 1 |
| Ahmed, RH | 1 |
| Gibbs, RB | 1 |
| Sozda, CN | 2 |
| Yelleswarapu, NK | 1 |
| Tay, JK | 1 |
| Fryer, WM | 1 |
| Shah, MA | 1 |
| Garcia, AN | 1 |
| Yu, J | 1 |
| Massucci, JL | 2 |
| Dixon, CE | 2 |
| Bolinger, BD | 1 |
| Wagner, AK | 1 |
| Westergom, BP | 1 |
| Malena, RR | 1 |
| Olsen, AS | 1 |
| Luthra, P | 1 |
| Panda, M | 1 |
| Aslam, HA | 2 |
8 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Brain Injuries
| Article | Year |
|---|---|
The role of 8-OH-DPAT on the rat neuronal apoptosis after diffuse brain injury coupled with secondary brain injury.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apoptosis; bcl-2-Associated X Protein; Brain Injuri | 2015 |
A delayed and chronic treatment regimen with the 5-HT1A receptor agonist 8-OH-DPAT after cortical impact injury facilitates motor recovery and acquisition of spatial learning.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Brain Injur | 2008 |
Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Injuries; Choline O-Acetylt | 2010 |
Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Injuries; Male; Maze Learni | 2012 |
Protective effects of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin against traumatic brain injury-induced cognitive deficits and neuropathology in adult male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Injuries; Cognition; Cognition Disorders; Dos | 2002 |
The therapeutic efficacy conferred by the 5-HT(1A) receptor agonist 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) after experimental traumatic brain injury is not mediated by concomitant hypothermia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acute Disease; Animals; Body Temperature; Brain Injuries; Ce | 2004 |
Acute treatment with the 5-HT(1A) receptor agonist 8-OH-DPAT and chronic environmental enrichment confer neurobehavioral benefit after experimental brain trauma.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Injuries; Cognition; Diseas | 2007 |
The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Injuries; Male; Maze Learni | 2007 |