8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Apnea in 5 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recurrent apneas are important causes of hospitalization and morbidity in newborns." | 7.79 | Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013) |
| " in doses that produce apnea." | 7.70 | Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000) |
| "Recurrent apneas are important causes of hospitalization and morbidity in newborns." | 3.79 | Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013) |
| "Intravenous bolus injection of morphine causes a vagal-mediated brief apnea (∼3 s), while continuous injection, via action upon central μ-opioid receptor (MOR), arrests ventilation (>20 s) that is eliminated by stimulating central 5-hydroxytryptamine 1A receptors (5HT(1A)Rs)." | 3.78 | 8-OH-DPAT abolishes the pulmonary C-fiber-mediated apneic response to fentanyl largely via acting on 5HT1A receptors in the nucleus tractus solitarius. ( Xu, F; Zhang, C; Zhang, Z; Zhuang, J, 2012) |
| " in doses that produce apnea." | 3.70 | Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuang, J | 1 |
| Zhang, Z | 1 |
| Zhang, C | 1 |
| Xu, F | 1 |
| Fournier, S | 2 |
| Steele, S | 1 |
| Julien, C | 1 |
| Gulemetova, R | 1 |
| Caravagna, C | 1 |
| Soliz, J | 1 |
| Bairam, A | 1 |
| Kinkead, R | 1 |
| Lalley, PM | 1 |
| Bischoff, AM | 1 |
| Richter, DW | 1 |
| Futuro-Neto, HA | 1 |
| Pires, JG | 1 |
| Gilbey, MP | 1 |
| Ramage, AG | 1 |
| Sahibzada, N | 1 |
| Ferreira, M | 1 |
| Wasserman, AM | 1 |
| Taveira-DaSilva, AM | 1 |
| Gillis, RA | 1 |
5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Apnea
| Article | Year |
|---|---|
8-OH-DPAT abolishes the pulmonary C-fiber-mediated apneic response to fentanyl largely via acting on 5HT1A receptors in the nucleus tractus solitarius.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apnea; Blood Pressure; Fentanyl; Heart Rate; Male; | 2012 |
Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Apnea; Corticosterone; Female; Hy | 2013 |
5-HT-1A receptor-mediated modulation of medullary expiratory neurones in the cat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Apnea; Cats; Electric Stimulatio | 1994 |
Evidence for the ability of central 5-HT1A receptors to modulate the vagal bradycardia induced by stimulating the upper airways of anesthetized rabbits with smoke.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Apnea; Atenolol; Blood Pressure; Buspir | 1993 |
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug I | 2000 |