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8-hydroxy-2-(di-n-propylamino)tetralin and Anoxemia

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Anoxemia in 11 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Research Excerpts

ExcerptRelevanceReference
"Recurrent apneas are important causes of hospitalization and morbidity in newborns."7.79Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013)
" We therefore examined the effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), an agonist of 5-HT1A and 5-HT7 receptors, and zacopride, an agonist of 5-HT4 receptors, to establish whether these ligands would reverse opioid-induced respiratory depression and hypoxia without affecting the immobilizing properties of the opioid drug etorphine."7.73Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. ( Fuller, A; Meyer, LC; Mitchell, D, 2006)
"We sought to confirm the effects of methylprednisolone (MP) on axonal depression induced by hypoxia, gamma-aminobutyric acid (GABA), and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide (8-OH-DPAT)."7.71Effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide. ( Ichikawa, T; Kodama, N; Matsumoto, M; Sakuma, J; Sasaki, T; Tiwari, P; Young, W, 2002)
"Recurrent apneas are important causes of hospitalization and morbidity in newborns."3.79Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013)
" We therefore examined the effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), an agonist of 5-HT1A and 5-HT7 receptors, and zacopride, an agonist of 5-HT4 receptors, to establish whether these ligands would reverse opioid-induced respiratory depression and hypoxia without affecting the immobilizing properties of the opioid drug etorphine."3.73Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. ( Fuller, A; Meyer, LC; Mitchell, D, 2006)
"We sought to confirm the effects of methylprednisolone (MP) on axonal depression induced by hypoxia, gamma-aminobutyric acid (GABA), and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide (8-OH-DPAT)."3.71Effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide. ( Ichikawa, T; Kodama, N; Matsumoto, M; Sakuma, J; Sasaki, T; Tiwari, P; Young, W, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kron, M1
Zimmermann, JL1
Dutschmann, M1
Funke, F1
Müller, M1
Fournier, S2
Steele, S1
Julien, C1
Gulemetova, R1
Caravagna, C1
Soliz, J1
Bairam, A1
Kinkead, R1
Sasaki, T1
Sakuma, J1
Ichikawa, T1
Matsumoto, M1
Tiwari, P1
Young, W1
Kodama, N1
Taylor, NC1
Li, A1
Nattie, EE1
Meyer, LC1
Fuller, A1
Mitchell, D1
Lalley, PM2
Bischoff, AM2
Richter, DW2
Schmidt-Garcon, P1
Pierrefiche, O1
Adayev, T1
El-Sherif, Y1
Barua, M1
Penington, NJ1
Banerjee, P1
Herman, JK2
O'Halloran, KD2
Bisgard, GE2
Chastrette, N1
Cespuglio, R1
Lin, YL1
Jouvet, M1

Other Studies

11 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Anoxemia

ArticleYear
Altered responses of MeCP2-deficient mouse brain stem to severe hypoxia.
    Journal of neurophysiology, 2011, Volume: 105, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Brain Stem;

2011
Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Jan-09, Volume: 33, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Apnea; Corticosterone; Female; Hy

2013
Effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide.
    Neurosurgery, 2002, Volume: 51, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Axons; gamma-Aminobutyric Acid; Hypoxia; In Vitro T

2002
Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats.
    The Journal of physiology, 2005, Jul-15, Volume: 566, Issue:Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Electroencephalography; Electromy

2005
Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Blood Pressure; Bridged Bicyclo Compoun

2006
Serotonin 1A-receptor activation suppresses respiratory apneusis in the cat.
    Neuroscience letters, 1994, May-19, Volume: 172, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Female; Hypoxia; Injections, Intraventricular

1994
Neurotransmitters and neuromodulators controlling the hypoxic respiratory response in anaesthetized cats.
    The Journal of physiology, 1999, Jan-15, Volume: 514 ( Pt 2)

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Anesthesia, General; Animals; Cats; Cell Membrane

1999
Agonist stimulation of the serotonin1A receptor causes suppression of anoxia-induced apoptosis via mitogen-activated protein kinase in neuronal HN2-5 cells.
    Journal of neurochemistry, 1999, Volume: 72, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Androstadienes; Animals; Apoptosis; Calcium; Calcium-Calmodu

1999
Serotonin and the hypoxic ventilatory response in awake goats.
    Advances in experimental medicine and biology, 2000, Volume: 475

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acclimatization; Animals; Carotid Body; Chemoreceptor Cells;

2000
Effect of 8-OH DPAT and ketanserin on the ventilatory acclimatization to hypoxia in awake goats.
    Respiration physiology, 2001, Volume: 124, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Analysis of Variance; Animals; Bl

2001
Proopiomelanocortin (POMC)-derived peptides and sleep in the rat. Part 2--Aminergic regulatory processes.
    Neuropeptides, 1990, Volume: 15, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; alpha-MSH; Animals; Apomorphine

1990