8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Anorexia in 10 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These studies investigated the involvement of the 5-HT1A receptor in mediating d-fenfluramine-induced anorexia in the rat." | 7.69 | Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype. ( Clifton, PG; Dourish, CT; Vickers, SP, 1996) |
| " In contrast, activation of somatodendritc 5-HT(1A) receptors in the raphe nuclei reduces forebrain 5-HT bioavailability and agonists of these receptors, including 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), reliably stimulate eating behavior." | 5.32 | Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT. ( Braver, M; Currie, PJ; Mirza, A; Sricharoon, K, 2004) |
| "These studies investigated the involvement of the 5-HT1A receptor in mediating d-fenfluramine-induced anorexia in the rat." | 3.69 | Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype. ( Clifton, PG; Dourish, CT; Vickers, SP, 1996) |
| " In contrast, activation of somatodendritc 5-HT(1A) receptors in the raphe nuclei reduces forebrain 5-HT bioavailability and agonists of these receptors, including 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), reliably stimulate eating behavior." | 1.32 | Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT. ( Braver, M; Currie, PJ; Mirza, A; Sricharoon, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miryala, CS | 1 |
| Maswood, N | 1 |
| Uphouse, L | 1 |
| Zendehdel, M | 1 |
| Taati, M | 1 |
| Jonaidi, H | 1 |
| Amini, E | 1 |
| Currie, PJ | 2 |
| Braver, M | 1 |
| Mirza, A | 1 |
| Sricharoon, K | 1 |
| Grignaschi, G | 1 |
| Mantelli, B | 1 |
| Samanin, R | 1 |
| Vickers, SP | 1 |
| Clifton, PG | 1 |
| Dourish, CT | 2 |
| Coscina, DV | 1 |
| Fletcher, PJ | 1 |
| Shimizu, N | 1 |
| Hori, T | 1 |
| Ogino, C | 1 |
| Kawanishi, T | 1 |
| Hayashi, Y | 1 |
| Hrupka, BJ | 1 |
| Langhans, W | 1 |
| Gietzen, DW | 1 |
| Rogers, QR | 1 |
| Leung, PM | 1 |
| Semon, B | 1 |
| Piechota, T | 1 |
| Hutson, PH | 1 |
| Kennett, GA | 1 |
| Curzon, G | 1 |
10 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Anorexia
| Article | Year |
|---|---|
Fluoxetine prevents 8-OH-DPAT-induced hyperphagia in Fischer inbred rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Eating; Estradiol; Female; Fluoxetine; Hy | 2011 |
The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anorex | 2012 |
Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Dose-Response Relationship, Drug; Feeding | 2004 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Model | 1993 |
Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Appetite Depressants; Appetitive Behavior | 1996 |
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus St | 1998 |
The 5-HT(1A) receptor agonist, 8-OH-DPAT, attenuates stress-induced anorexia in conjunction with the suppression of hypothalamic serotonin release in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Eating; Hypothalamic Area, Lateral; Immob | 2000 |
A role for serotonin in lipopolysaccharide-induced anorexia in rats.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Cisterna Magna; | 2001 |
Serotonin and feeding responses of rats to amino acid imbalance: initial phase.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acids; Animals; Anorexia; Die | 1987 |
8-OH-DPAT-induced hyperphagia: its neural basis and possible therapeutic relevance.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Biogenic Amines; Brain; Feeding Behavior; | 1986 |