8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Anorexia Nervosa in 5 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The role of 5-HT1A receptors in nutrient intake was also examined in a dose-response study (100-700 microg/kg body weight) of 8-hydroxy-2-(di-n-propylamino) tetralin (DPAT) in an acute restraint model." | 1.31 | Effects of restraint stress and serotonin on macronutrient selection: a rat model of stress-induced anorexia. ( Wang, SW, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butt, I | 1 |
| Hong, A | 1 |
| Di, J | 1 |
| Aracena, S | 1 |
| Banerjee, P | 1 |
| Shen, CH | 1 |
| Haleem, DJ | 1 |
| Atchley, DP | 1 |
| Eckel, LA | 1 |
| Grignaschi, G | 1 |
| Mantelli, B | 1 |
| Samanin, R | 1 |
| Wang, SW | 1 |
5 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Anorexia Nervosa
| Article | Year |
|---|---|
The effects of serotonin1A receptor on female mice body weight and food intake are associated with the differential expression of hypothalamic neuropeptides and the GABAA receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia Nervosa; Body Weight; Bulimia Nervosa; Fee | 2014 |
Exaggerated feedback control decreases brain serotonin concentration and elicits hyperactivity in a rat model of diet-restriction-induced anorexia nervosa.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia Nervosa; Brain Chemistry; Feedback, Physio | 2009 |
Treatment with 8-OH-DPAT attenuates the weight loss associated with activity-based anorexia in female rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia Nervosa; Body Temperature; Eating; Estrus; | 2006 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Model | 1993 |
Effects of restraint stress and serotonin on macronutrient selection: a rat model of stress-induced anorexia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anorexia Nervosa; Brain Chemi | 2002 |