8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Anankastic Personality in 17 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preliminary clinical findings, supported by preclinical studies employing behavioral paradigms such as marble burying, suggest that psilocybin may be effective in treating obsessive-compulsive disorder." | 8.31 | Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder. ( Botvinnik, A; Lerer, B; Lifschytz, T; Lotan, A; Saban, M; Salama, A; Shahar, O; Singh, S; Wolf, G; Yakobi, C, 2023) |
| " In the present study, we examined the effect of perospirone on marble-burying behavior, which has been considered an animal model of obsessive-compulsive disorder (OCD), compared with the effects of other antipsychotics such as haloperidol and risperidone." | 7.73 | Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. ( Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R, 2005) |
| " Chronic administration of AKBA at 50 mg/kg and 100 mg/kg p." | 5.91 | Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations. ( Chhabra, S; Khan, Z; Mehan, S; Sethi, P, 2023) |
| "Preliminary clinical findings, supported by preclinical studies employing behavioral paradigms such as marble burying, suggest that psilocybin may be effective in treating obsessive-compulsive disorder." | 4.31 | Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder. ( Botvinnik, A; Lerer, B; Lifschytz, T; Lotan, A; Saban, M; Salama, A; Shahar, O; Singh, S; Wolf, G; Yakobi, C, 2023) |
| " In the present study, we examined the effect of perospirone on marble-burying behavior, which has been considered an animal model of obsessive-compulsive disorder (OCD), compared with the effects of other antipsychotics such as haloperidol and risperidone." | 3.73 | Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. ( Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R, 2005) |
| " Chronic administration of AKBA at 50 mg/kg and 100 mg/kg p." | 1.91 | Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations. ( Chhabra, S; Khan, Z; Mehan, S; Sethi, P, 2023) |
| "Melatonin has beneficial effects on various illnesses, including Alzheimer's, Parkinson's, and depression, indicating its potential efficacy in treating OCD." | 1.91 | Melatonin-mediated IGF-1/GLP-1 activation in experimental OCD rats: Evidence from CSF, blood plasma, brain and in-silico investigations. ( Giri, A; Gupta, GD; Khan, Z; Mehan, S; Narula, AS, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, S | 1 |
| Botvinnik, A | 1 |
| Shahar, O | 1 |
| Wolf, G | 1 |
| Yakobi, C | 1 |
| Saban, M | 1 |
| Salama, A | 1 |
| Lotan, A | 1 |
| Lerer, B | 1 |
| Lifschytz, T | 1 |
| Sethi, P | 1 |
| Mehan, S | 2 |
| Khan, Z | 2 |
| Chhabra, S | 1 |
| Giri, A | 1 |
| Gupta, GD | 1 |
| Narula, AS | 1 |
| Janikova, M | 1 |
| Mainerova, K | 1 |
| Vojtechova, I | 1 |
| Petrasek, T | 1 |
| Svoboda, J | 1 |
| Stuchlik, A | 1 |
| Tucci, MC | 1 |
| Dvorkin-Gheva, A | 2 |
| Johnson, E | 1 |
| Cheon, P | 1 |
| Taji, L | 1 |
| Agarwal, A | 1 |
| Foster, J | 1 |
| Szechtman, H | 2 |
| S N, U | 1 |
| J M, V | 1 |
| N S, J | 1 |
| P V, D | 1 |
| Albelda, N | 1 |
| Joel, D | 1 |
| Shanahan, NA | 1 |
| Velez, LP | 1 |
| Masten, VL | 1 |
| Dulawa, SC | 1 |
| Alkhatib, AH | 1 |
| Olvera-Hernández, S | 1 |
| Chavira, R | 1 |
| Fernández-Guasti, A | 4 |
| Ulloa, RE | 2 |
| Nicolini, H | 2 |
| van Kuyck, K | 1 |
| Demeulemeester, H | 2 |
| Feys, H | 2 |
| De Weerdt, W | 2 |
| Dewil, M | 1 |
| Tousseyn, T | 1 |
| De Sutter, P | 2 |
| Gybels, J | 2 |
| Bogaerts, K | 1 |
| Dom, R | 1 |
| Nuttin, B | 2 |
| Matsushita, M | 1 |
| Egashira, N | 1 |
| Harada, S | 1 |
| Okuno, R | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Nishimura, R | 1 |
| Fujiwara, M | 1 |
| Agrati, D | 1 |
| Reyes, R | 1 |
| Ferreira, A | 1 |
| Goris, I | 1 |
| Zwaenepoel, I | 1 |
| Plets, C | 1 |
| Yadin, E | 1 |
| Friedman, E | 1 |
| Bridger, WH | 1 |
1 review available for 8-hydroxy-2-(di-n-propylamino)tetralin and Anankastic Personality
| Article | Year |
|---|---|
Animal models of obsessive-compulsive disorder: exploring pharmacology and neural substrates.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Deep Brain Stimulation; Disease Models, Animal; Dop | 2012 |
16 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Anankastic Personality
| Article | Year |
|---|---|
Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Escitalopram; Hallucinogens; Male; Mice; | 2023 |
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Fluvoxamine; NF-E2-Related Factor | 2023 |
Melatonin-mediated IGF-1/GLP-1 activation in experimental OCD rats: Evidence from CSF, blood plasma, brain and in-silico investigations.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Glucagon-Like Peptide 1; Insulin-Like Growth | 2023 |
Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Male; Mem | 2021 |
Performance of compulsive behavior in rats is not a unitary phenomenon - validation of separate functional components in compulsive checking behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Compulsive Behavior; Disease Models, Animal; Male; | 2014 |
Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Dehydroepia | 2009 |
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic beta-Antagonists; Adrenergi | 2011 |
Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Compulsive Behavior; Disea | 2013 |
Sex- and endocrine-stage-differences in middle-aged rats in an animal model of OCD.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Disease Models, | 2013 |
Age differences in the sensitivity to clomipramine in an animal model of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Antidepressive Agents, Tricyclic; Clomiprami | 2003 |
Effects of electrical stimulation or lesion in nucleus accumbens on the behaviour of rats in a T-maze after administration of 8-OH-DPAT or vehicle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Electric | 2003 |
Sex differences on spontaneous alternation in prepubertal rats: implications for an animal model of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Behavior, Animal; Disease Models, Animal; Fe | 2004 |
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Mod | 2005 |
Ovarian steroids counteract serotonergic drugs actions in an animal model of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Estradiol; Estrous Cycle; Female; Fluoxetine; Obses | 2006 |
Effect of the serotonin agonist 8-OH-DPAT on the sensorimotor system of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Disease Models, Animal; Male; Obsessive-Compulsive | 2001 |
Spontaneous alternation behavior: an animal model for obsessive-compulsive disorder?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Fluoxetin | 1991 |