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8-hydroxy-2-(di-n-propylamino)tetralin and Amnesia

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Amnesia in 9 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
"The effects of minaprine on cycloheximide-induced amnesia were investigated in a step-down passive avoidance task in mice."7.67Effect of minaprine on cycloheximide-induced amnesia in mice. ( Kameyama, T; Kawashima, K; Nabeshima, T, 1989)
"Post-training and/or pre-test 8-OH-DPAT, AS19 and muscimol induced amnesia."3.91Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus. ( Jafari-Sabet, M; Nemati, S; Torab, M, 2019)
"The effects of minaprine on cycloheximide-induced amnesia were investigated in a step-down passive avoidance task in mice."3.67Effect of minaprine on cycloheximide-induced amnesia in mice. ( Kameyama, T; Kawashima, K; Nabeshima, T, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Jafari-Sabet, M2
Amiri, S1
Aghamiri, H1
Fatahi, N1
Nemati, S1
Torab, M1
Perez-GarcĂ­a, G1
Meneses, A2
Millan, MJ1
Gobert, A1
Roux, S1
Porsolt, R1
Carli, M2
Di Cara, B1
Jaffard, R1
Rivet, JM1
Lestage, P1
Mocaer, E1
Peglion, JL1
Dekeyne, A1
Kawakubo, H1
Takagi, S1
Yamaura, Y1
Katoh, S1
Ishimoto, Y1
Nagatani, T1
Mochizuki, D1
Kamata, T1
Sasaki, Y1
Tatarczynska, E1
Cervo, L1
Samanin, R1
Mendelson, SD1
Quartermain, D1
Francisco, T1
Shemer, A1
Liang, KC1
Nabeshima, T1
Kawashima, K1
Kameyama, T1

Other Studies

9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Amnesia

ArticleYear
Cross state-dependent memory retrieval between cannabinoid CB1 and serotonergic 5-HT1A receptor agonists in the mouse dorsal hippocampus.
    Neurobiology of learning and memory, 2022, Volume: 192

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; Cannabinoid Receptor A

2022
Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus.
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; CA1 Region, Hippocampa

2019
Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia.
    Behavioural brain research, 2008, Dec-16, Volume: 195, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Behavior, Animal; Cholinergic Antagonists;

2008
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Aging; Amnesia; Animals; Dialysis; Discrimina

2004
(R)-1,2,3,4-tetrahydro[1]benzothieno[2,3-c]pyridines: novel optically active compounds with strong 5-HT1A receptor binding ability exhibiting anticonflict activity and lessening of memory impairment.
    Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; C

1993
Stimulation of hippocampal 5-HT1A receptors causes amnesia and anxiolytic-like but not antidepressant-like effects in the rat.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Anti-Anxiety Agents; Antidepressive Agents

1993
5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism.
    European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Amphetamine; Animals; Avoidance Learning; Drug Admi

1993
Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors.
    The European journal of neuroscience, 1999, Volume: 11, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Amygdala; Animals; Avoidance Learning; Behavior, An

1999
Effect of minaprine on cycloheximide-induced amnesia in mice.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; Cycloheximide; Drug In

1989