8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Alcoholism in 8 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, to evaluate the functional status of the autoreceptors under control conditions and after withdrawal from chronic ethanol, the selective serotonin-1A receptor agonist 8-hydroxy-(2-di-n-propylamino)tetralin was administered intravenously in cumulative doses (1-16 microg/kg) and dose-response curves were generated for both groups." | 1.30 | Effects of acute, chronic ethanol and withdrawal on dorsal raphe neurons: electrophysiological studies. ( Diana, M; Gessa, G; Muntoni, AL; Pistis, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burnett, EJ | 1 |
| Grant, KA | 1 |
| Davenport, AT | 1 |
| Hemby, SE | 1 |
| Friedman, DP | 1 |
| Tanaka, K | 1 |
| Kunishige-Yamamoto, A | 1 |
| Hashimoto, H | 1 |
| Shintani, N | 1 |
| Hayata, A | 1 |
| Baba, A | 1 |
| Compagnon, P | 1 |
| Ernouf, D | 1 |
| Narcisse, G | 1 |
| Daoust, M | 1 |
| Pistis, M | 1 |
| Muntoni, AL | 1 |
| Gessa, G | 1 |
| Diana, M | 1 |
| Pandey, SC | 1 |
| Piano, MR | 1 |
| Schwertz, DW | 1 |
| Davis, JM | 1 |
| Pandey, GN | 1 |
| Overstreet, DH | 1 |
| Rezvani, AH | 1 |
| Janowsky, DS | 1 |
| Ulrichsen, J | 1 |
| Wong, DT | 1 |
| Threlkeld, PG | 1 |
| Lumeng, L | 1 |
| Li, TK | 1 |
1 review available for 8-hydroxy-2-(di-n-propylamino)tetralin and Alcoholism
| Article | Year |
|---|---|
Serotonin in animal models of alcoholism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Disease Models, Animal; Male; Mice; Rat | 1993 |
7 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Alcoholism
| Article | Year |
|---|---|
The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Aminopyridines; Animals; Autoradiography; Centra | 2014 |
Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Behavior, Animal; Conditioning, Classic | 2010 |
Effects of acute, chronic ethanol and withdrawal on dorsal raphe neurons: electrophysiological studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Alcoholism; Analysis of Variance; Animals; | 1997 |
Effect of ethanol administration and withdrawal on serotonin receptor subtypes and receptor-mediated phosphoinositide hydrolysis in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholism; Animals; Calcimycin | 1992 |
Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Alcoholism; Animals; Arousal; Avoidance Le | 1992 |
Alterations in serotonin receptor subtypes in ethanol-dependent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcohol | 1991 |
Higher density of serotonin-1A receptors in the hippocampus and cerebral cortex of alcohol-preferring P rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Cell Membrane; Cerebral Cortex; Disease | 1990 |