8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Alcohol Abuse in 8 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, to evaluate the functional status of the autoreceptors under control conditions and after withdrawal from chronic ethanol, the selective serotonin-1A receptor agonist 8-hydroxy-(2-di-n-propylamino)tetralin was administered intravenously in cumulative doses (1-16 microg/kg) and dose-response curves were generated for both groups." | 1.30 | Effects of acute, chronic ethanol and withdrawal on dorsal raphe neurons: electrophysiological studies. ( Diana, M; Gessa, G; Muntoni, AL; Pistis, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burnett, EJ | 1 |
| Grant, KA | 1 |
| Davenport, AT | 1 |
| Hemby, SE | 1 |
| Friedman, DP | 1 |
| Tanaka, K | 1 |
| Kunishige-Yamamoto, A | 1 |
| Hashimoto, H | 1 |
| Shintani, N | 1 |
| Hayata, A | 1 |
| Baba, A | 1 |
| Compagnon, P | 1 |
| Ernouf, D | 1 |
| Narcisse, G | 1 |
| Daoust, M | 1 |
| Pistis, M | 1 |
| Muntoni, AL | 1 |
| Gessa, G | 1 |
| Diana, M | 1 |
| Pandey, SC | 1 |
| Piano, MR | 1 |
| Schwertz, DW | 1 |
| Davis, JM | 1 |
| Pandey, GN | 1 |
| Overstreet, DH | 1 |
| Rezvani, AH | 1 |
| Janowsky, DS | 1 |
| Ulrichsen, J | 1 |
| Wong, DT | 1 |
| Threlkeld, PG | 1 |
| Lumeng, L | 1 |
| Li, TK | 1 |
1 review available for 8-hydroxy-2-(di-n-propylamino)tetralin and Alcohol Abuse
| Article | Year |
|---|---|
Serotonin in animal models of alcoholism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Disease Models, Animal; Male; Mice; Rat | 1993 |
7 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Alcohol Abuse
| Article | Year |
|---|---|
The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Aminopyridines; Animals; Autoradiography; Centra | 2014 |
Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Behavior, Animal; Conditioning, Classic | 2010 |
Effects of acute, chronic ethanol and withdrawal on dorsal raphe neurons: electrophysiological studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Alcoholism; Analysis of Variance; Animals; | 1997 |
Effect of ethanol administration and withdrawal on serotonin receptor subtypes and receptor-mediated phosphoinositide hydrolysis in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholism; Animals; Calcimycin | 1992 |
Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Alcoholism; Animals; Arousal; Avoidance Le | 1992 |
Alterations in serotonin receptor subtypes in ethanol-dependent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcohol | 1991 |
Higher density of serotonin-1A receptors in the hippocampus and cerebral cortex of alcohol-preferring P rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Animals; Cell Membrane; Cerebral Cortex; Disease | 1990 |