8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Air Sickness in 9 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doses of naloxone far below those which elicit emesis increase the sensitivity to motion sickness." | 7.85 | Effects of naloxone on motion sickness in cats alone and with broad spectrum antiemetics. ( Lucot, JB, 2017) |
| " A supplementary experiment revealed that lorazepam suppressed motion sickness at a dose that produced ataxia, but did not suppress xylazine-induced emesis." | 7.67 | 8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine. ( Crampton, GH; Lucot, JB, 1989) |
| "Doses of naloxone far below those which elicit emesis increase the sensitivity to motion sickness." | 3.85 | Effects of naloxone on motion sickness in cats alone and with broad spectrum antiemetics. ( Lucot, JB, 2017) |
| " Flesinoxan produced a dose-dependent suppression of motion sickness and also reduced xylazine-induced emesis at higher doses." | 3.69 | Antiemetic effects of flesinoxan in cats: comparisons with 8-hydroxy-2-(di-n-propylamino)tetralin. ( Lucot, JB, 1994) |
| "The antiemetic effects of six serotonergic 5-HT1A-receptor agonists, 8-hydroxy-2-(di-n-propylamino)tetrarin (8-OH-DPAT), 4-(4-[4-(2-pyrimidinyl)piperazin-1-yl]butyl)-2,3,4,5- tetrahydro-1,4-benzoxazepine-3,5-dione (SUN8399), buspirone, gepirone, ipsapirone and tandospirone, against motion sickness were investigated in Suncus murinus." | 3.69 | Antiemetic effects of serotonergic 5-HT1A-receptor agonists in Suncus murinus. ( Matsuki, N; Okada, F; Saito, H; Torii, Y, 1994) |
| "This investigation evaluated the antagonist properties of (-)propranolol, (+)propranolol, metergoline and BMY 7378 on the known effect of 8-OH-DPAT (DPAT) to decrease motion sickness in cats." | 3.68 | Effects of serotonin antagonists on motion sickness and its suppression by 8-OH-DPAT in cats. ( Lucot, JB, 1990) |
| " A supplementary experiment revealed that lorazepam suppressed motion sickness at a dose that produced ataxia, but did not suppress xylazine-induced emesis." | 3.67 | 8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine. ( Crampton, GH; Lucot, JB, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lucot, JB | 7 |
| Brame, RE | 2 |
| Garrett, TL | 1 |
| Pfadenhauer, EH | 1 |
| Kumar, A | 1 |
| Fick, DB | 1 |
| Helton, DR | 1 |
| Okada, F | 2 |
| Torii, Y | 1 |
| Saito, H | 1 |
| Matsuki, N | 2 |
| Andrews, PL | 1 |
| Woods, AJ | 1 |
| Hagiwara, H | 1 |
| Kakaimoto, S | 1 |
| Toyoda, M | 1 |
| Crampton, GH | 2 |
9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Air Sickness
| Article | Year |
|---|---|
The broad-spectrum antiemetic effects ETI-385 result from stimulation of 5-HT1A and 5-HT1D receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Cats; Disease Models, Animal; Dose-Res | 2014 |
Effects of naloxone on motion sickness in cats alone and with broad spectrum antiemetics.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Cats; Dose-Response Relationship, Drug | 2017 |
Guamanian Suncus murinus responsiveness to emetic stimuli and the antiemetic effects of 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Female; Male; Motion Sickness; Shrews; | 2011 |
Antiemetic effects of flesinoxan in cats: comparisons with 8-hydroxy-2-(di-n-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiemetics; Behavior, Animal | 1994 |
Antiemetic effects of serotonergic 5-HT1A-receptor agonists in Suncus murinus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Buspirone; Dose-Response Relationship, | 1994 |
The emetic and anti-emetic effects of the capsaicin analogue resiniferatoxin in Suncus murinus, the house musk shrew.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Abdomen; Animals; Animals, Newborn; Antiemetics; Behavior, A | 2000 |
8-OH-DPAT does not interfere with habituation to motion-induced emesis in cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Habituation, Psychophysiologic; Motion Sickne | 1991 |
Effects of serotonin antagonists on motion sickness and its suppression by 8-OH-DPAT in cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Dose-Response Relationship, Drug; Ergolines; | 1990 |
8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Cisplatin; Dose-Response Relationship, Drug; | 1989 |