8-epi-prostaglandin-f2alpha and Fibromyalgia

8-epi-prostaglandin-f2alpha has been researched along with Fibromyalgia* in 1 studies

Other Studies

1 other study(ies) available for 8-epi-prostaglandin-f2alpha and Fibromyalgia

ArticleYear
Asymmetric dimethylarginine (ADMA) levels are increased in patients with fibromyalgia: correlation with tumor necrosis factor-α (TNF-α) and 8-iso-prostaglandin F(2α) (8-iso-PGF(2α)).
    Clinical biochemistry, 2011, Volume: 44, Issue:5-6

    The aim of the study was to investigate serum levels of asymmetric dimethylarginine (ADMA), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and plasma levels of 8-iso-prostaglandin F(2α) (8-iso-PGF(2α)) in patients with fibromyalgia.. Twenty-seven patients with fibromyalgia and twenty healthy controls were enrolled in this study. ADMA, TNF-α, IL-6 and 8-iso-PGF(2α) levels were measured by enzyme-linked immunosorbent assay (ELISA).. Serum levels of ADMA and TNF-α and plasma levels 8-iso-PGF(2α) were significantly increased in patients with fibromyalgia compared to controls. However, no significant difference was observed in IL-6 levels between the two groups. ADMA concentrations were positively correlated with TNF-α and 8-iso-PGF(2α) levels in patients with fibromyalgia.. This is the first study reporting that ADMA levels are significantly elevated in patients with fibromyalgia in association with increased 8-iso-PGF(2α) and TNF-α concentrations. Thereby, ADMA could be suggested as a reliable marker of endothelial dysfunction in patients with fibromyalgia.

    Topics: Adult; Arginine; Dinoprost; Female; Fibromyalgia; Humans; Male; Middle Aged; Surveys and Questionnaires; Tumor Necrosis Factor-alpha

2011