8-cyclopentyl-1,3-dimethylxanthine has been researched along with Hypoxia in 11 studies
8-cyclopentyl-1,3-dimethylxanthine: prolongs epileptic seizures in rats
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Presynaptic depression of evoked EPSCs by hypoxia or adenosine was significantly larger in alpha-Syn knockout than in wild-type mice, further supporting the hypothesis of regulation of synaptic transmission by alpha-Syn." | 3.72 | Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice. ( Ceña, V; Fariñas, I; González-García, C; Martín, ED; Milán, M, 2004) |
| "In an in vitro preparation of the intact carotid body (CB) of the rabbit, adenosine (100 microM) inhibited hypoxia-induced catecholamine release by 25%." | 3.70 | Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells. ( Almaraz, L; Gonzalez, C; Rocher, A, 1999) |
| "Endogenous adenosine depresses synaptic transmission in rat hippocampal slices during periods of hypoxia, a potentially neuroprotective cellular response that is attenuated by the adenosine antagonist 8-cyclopentyltheophylline." | 3.68 | Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: an anatomical and behavioral study. ( Boissard, CG; Gribkoff, VK; Lindner, MD, 1992) |
| "Adenosine serves as a homeostatic factor, regulating hippocampal activity through A(1) receptor-mediated inhibition." | 1.35 | Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus. ( Hamilton, JB; Lancaster, DM; Patel, N; Pietersen, AN; Vreugdenhil, M, 2009) |
| "During anoxia, however, these antagonists provoked maximal efflux of K+ (anoxic depolarization)." | 1.29 | Adenosine, a "retaliatory" metabolite, promotes anoxia tolerance in turtle brain. ( Lutz, PL; Pérez-Pinzón, MA; Rosenthal, M; Sick, TJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pietersen, AN | 1 |
| Lancaster, DM | 1 |
| Patel, N | 1 |
| Hamilton, JB | 1 |
| Vreugdenhil, M | 1 |
| Lobner, D | 1 |
| Fowler, JC | 2 |
| Gervitz, LM | 2 |
| Hamilton, ME | 1 |
| Walker, JA | 1 |
| Davies, DG | 1 |
| Omidvar, K | 1 |
| Martín, ED | 1 |
| González-García, C | 1 |
| Milán, M | 1 |
| Fariñas, I | 1 |
| Ceña, V | 1 |
| Arrigoni, E | 1 |
| Crocker, AJ | 1 |
| Saper, CB | 1 |
| Greene, RW | 1 |
| Scammell, TE | 1 |
| Adén, U | 1 |
| Lindström, K | 1 |
| Bona, E | 1 |
| Hagberg, H | 1 |
| Fredholm, BB | 1 |
| Pérez-Pinzón, MA | 1 |
| Lutz, PL | 1 |
| Sick, TJ | 1 |
| Rosenthal, M | 1 |
| Broadley, KJ | 1 |
| Maddock, HL | 1 |
| Rocher, A | 1 |
| Gonzalez, C | 1 |
| Almaraz, L | 1 |
| Boissard, CG | 1 |
| Lindner, MD | 1 |
| Gribkoff, VK | 1 |
11 other studies available for 8-cyclopentyl-1,3-dimethylxanthine and Hypoxia
| Article | Year |
|---|---|
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Varianc | 2009 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agon | 2002 |
Systemic hypoxia and the depression of synaptic transmission in rat hippocampus after carotid artery occlusion.
Topics: Adenosine; Animals; Carotid Arteries; Cerebrovascular Circulation; Electrophysiology; Excitatory Pos | 2003 |
The effect of acute hypoxemia and hypotension on adenosine-mediated depression of evoked hippocampal synaptic transmission.
Topics: Acute Disease; Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Carotid | 2003 |
Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.
Topics: 4-Aminopyridine; Adenosine; alpha-Synuclein; Analgesics; Anesthetics, Local; Animals; Blotting, West | 2004 |
Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia.
Topics: Adenosine A1 Receptor Antagonists; Animals; Dependovirus; Electric Stimulation; Excitatory Postsynap | 2005 |
Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia.
Topics: Animals; Animals, Newborn; Brain; Cerebral Cortex; Down-Regulation; Female; Guanosine Triphosphate; | 1994 |
Adenosine, a "retaliatory" metabolite, promotes anoxia tolerance in turtle brain.
Topics: Adenosine; Animals; Brain; Cerebellum; Hypoxia; In Vitro Techniques; Purinergic Antagonists; Theophy | 1993 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; In | 1996 |
Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channel | 1999 |
Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: an anatomical and behavioral study.
Topics: Animals; Avoidance Learning; Cell Death; Cognition; Hippocampus; Hypoxia; Male; Memory; Motor Activi | 1992 |