8-bromo cyclic adenosine monophosphate and Cell Transformation, Neoplastic

8-bromo cyclic adenosine monophosphate has been researched along with Cell Transformation, Neoplastic in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's16 (57.14)18.2507
2000's5 (17.86)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borghi, MO; Dicitore, A; Grassi, ES; Negri, I; Persani, L; Vitale, G1
Aandahl, EM; Brudvik, KW; Paulsen, JE; Roald, B; Taskén, K1
Arnaldi, G; Beck-Peccoz, P; Bondioni, S; Bosari, S; Ferrero, S; Lania, AG; Mantovani, G; Pedroni, C; Pellegrini, C; Peverelli, E; Spada, A; Vicentini, L1
Chiffer, RC; Leuba, SH; Rodriguez-Collazo, P; Smith, CL; Snyder, SK; Zlatanova, J1
Chou, JY2
Patterson, D; Puck, TT; Schonberg, S1
Budillon, A; Cereseto, A; Cho-Chung, YS; Clair, T; Kondrashin, A; Merlo, G; Nesterova, M1
Iwamoto, Y; Martin, GR; Nemeth, G; Reich, R; Yamada, Y1
Baldassarre, G; Bianco, AR; Bianco, C; Ciardiello, F; Pepe, S; Ruggiero, A; Selvam, MP; Tortora, G1
Israel, L; Mainguene, C; Nehme, A; Planchon, P; Prevost, G; Salle, V; Spanakis, E; Starzec, AB; Valette, A; Veber, N1
Chen, J; Iyengar, R1
Becchis, M; Berta, L; Catalano, MG; Comba, A; Fazzari, A; Fissore, F; Fortunati, N; Frairia, R1
Ciardiello, F; Tortora, G1
Krystosek, A1
Cho-Chung, YS; Murata, T; Noguchi, K1
Halbert, CL; Kavanagh, TJ; Lymp, J; Mendez, AJ; Oram, JF1
Grotendorst, GR; Kothapalli, D1
Memin, E; Molina, CA; Razavi, R; Schlotter, F; Yehia, G1
Chanoine, JP; Compagnone, NA; Mellon, SH; Wong, AC1
Amsterdam, A; Billheimer, JT; Rennert, H; Strauss, JF1
Ally, S; Cho-Chung, YS; Ciardiello, F; Clair, T; Kim, N; Salomon, DS; Tortora, G1
Krystosek, A; Puck, TT1
Bartholdi, M; Haag, M; Johnson, R; Krystosek, A; Puck, TT1
Lin, MC; Wu, YY1
Aloj, SM; Bifulco, M; Laezza, C; Santillo, M; Tedesco, I; Zarrilli, R1
Berg, KL; Foster, DA; Joseph, C; Qureshi, SA; Spangler, R1
Bos, JL; Burgering, BM; Maassen, JA; Snijders, AJ; van der Eb, AJ1

Reviews

1 review(s) available for 8-bromo cyclic adenosine monophosphate and Cell Transformation, Neoplastic

ArticleYear
Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinases; ErbB Receptors; Genes, ras; Humans; Neoplasms; Transforming Growth Factor alpha

1998

Other Studies

27 other study(ies) available for 8-bromo cyclic adenosine monophosphate and Cell Transformation, Neoplastic

ArticleYear
8-Cl-cAMP and PKA I-selective cAMP analogs effectively inhibit undifferentiated thyroid cancer cell growth.
    Endocrine, 2017, Volume: 56, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP; Humans; Phosphorylation; Signal Transduction; Thyroid Gland; Thyroid Neoplasms

2017
Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice.
    Molecular cancer, 2011, Dec-15, Volume: 10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Active Transport, Cell Nucleus; Adenomatous Polyposis Coli Protein; Animals; beta Catenin; Cell Nucleus; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Down-Regulation; HCT116 Cells; Humans; Mice; Proto-Oncogene Proteins c-myc; Thionucleotides

2011
Different expression of protein kinase A (PKA) regulatory subunits in cortisol-secreting adrenocortical tumors: relationship with cell proliferation.
    Experimental cell research, 2008, Jan-01, Volume: 314, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Base Sequence; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydrocortisone; Up-Regulation

2008
cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines.
    Experimental cell research, 2008, Jan-01, Volume: 314, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Histones; Humans; Mammary Neoplasms, Animal; Methylation; Mice; Phosphorylation; Regulatory Elements, Transcriptional; Signal Transduction

2008
Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Choriocarcinoma; Chorionic Gonadotropin; Cyclic AMP; Deoxyuracil Nucleotides; Female; Fluorodeoxyuridylate; Humans; Pregnancy; Pregnancy-Specific beta 1-Glycoproteins; Tretinoin; Uterine Neoplasms

1982
Role of cyclic adenosine 3',5'-monophosphate in differentiation of fetal liver cells in vitro.
    Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1983, Volume: 4, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Albumins; alpha-Fetoproteins; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Cyclic AMP; Fetus; Liver; Rats; Transferrin

1983
Resistance of Chinese hamster ovary cell chromatin to endonuclease digestion. I. Reversal by cAMP.
    Experimental cell research, 1983, Apr-15, Volume: 145, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Chromatin; Cricetinae; Cyclic AMP; Deoxyribonuclease I; DNA; Endodeoxyribonucleases; Female; Ovary

1983
Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Nov-07, Volume: 92, Issue:23

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Base Sequence; Cell Compartmentation; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Sorting Signals

1995
Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts.
    Clinical & experimental metastasis, 1993, Volume: 11, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Transformation, Neoplastic; Chemotaxis; Collagen; Collagenases; Drug Combinations; Female; Fibroblasts; Gene Expression; Genes, ras; In Vitro Techniques; Laminin; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Proteoglycans; Proto-Oncogene Proteins p21(ras); Transfection

1993
Reduction of RI alpha subunit of cAMP-dependent protein kinase expression induces growth inhibition of human mammary epithelial cells transformed by TGF-alpha, c-Ha-ras, and c-erbB-2 genes.
    Annals of the New York Academy of Sciences, 1993, Nov-30, Volume: 698

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Base Sequence; Breast; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Epithelium; ErbB Receptors; Female; Genes, ras; Humans; Macromolecular Substances; Molecular Sequence Data; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Receptor, ErbB-2; Transforming Growth Factor alpha

1993
Proliferative responses of epithelial cells to 8-bromo-cyclic AMP and to a phorbol ester change during breast pathogenesis.
    Journal of cellular physiology, 1994, Volume: 161, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biopsy; Breast; Breast Neoplasms; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cholera Toxin; Epithelium; Humans; Reference Values; Tetradecanoylphorbol Acetate; Time Factors

1994
Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s.
    Science (New York, N.Y.), 1994, Mar-04, Volume: 263, Issue:5151

    Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Genes, ras; GTP-Binding Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Transfection

1994
Sex steroid binding protein exerts a negative control on estradiol action in MCF-7 cells (human breast cancer) through cyclic adenosine 3',5'-monophosphate and protein kinase A.
    Endocrinology, 1996, Volume: 137, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Carrier Proteins; Cell Division; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Humans; Intracellular Signaling Peptides and Proteins; Peptide Fragments; Pregnancy; Sex Hormone-Binding Globulin; Tumor Cells, Cultured

1996
Repositioning of human interphase chromosomes by nucleolar dynamics in the reverse transformation of HT1080 fibrosarcoma cells.
    Experimental cell research, 1998, May-25, Volume: 241, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Binding Sites; Cell Division; Cell Nucleolus; Cell Transformation, Neoplastic; Chromosome Mapping; Chromosomes; DNA Probes; Fibrosarcoma; Humans; In Situ Hybridization, Fluorescence; Interphase; Kinetochores; Phenotype; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured

1998
8-chloroadenosine 3',5'-monophosphate (8-Cl-cAMP) selectively eliminates protein kinase A type I to induce growth inhibition in c-ras-transformed fibroblasts.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:8

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Genes, ras; Mice; Oncogene Protein p21(ras)

1998
Reduction in apolipoprotein-mediated removal of cellular lipids by immortalization of human fibroblasts and its reversion by cAMP: lack of effect with Tangier disease cells.
    Journal of lipid research, 1999, Volume: 40, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Apolipoprotein A-I; Apolipoproteins; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Culture Media, Serum-Free; Cyclic AMP; Fibroblasts; Homozygote; Humans; Kinetics; Membrane Lipids; Oncogenes; Papillomaviridae; Phospholipids; Signal Transduction; Skin; Tangier Disease

1999
CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts.
    Journal of cellular physiology, 2000, Volume: 182, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Transformation, Neoplastic; Connective Tissue Growth Factor; Cyclic AMP; Cyclin A; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Fibroblasts; Growth Substances; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Microtubule-Associated Proteins; Mitogens; Phosphorylation; Promoter Regions, Genetic; Rats; Retinoblastoma Protein; Transforming Growth Factor beta; Tumor Suppressor Proteins; Up-Regulation

2000
The expression of inducible cAMP early repressor (ICER) is altered in prostate cancer cells and reverses the transformed phenotype of the LNCaP prostate tumor cell line.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP Response Element Modulator; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; Prostatic Neoplasms; Repressor Proteins; Signal Transduction; Transfection; Tumor Cells, Cultured

2001
Modulation of steroidogenesis by selenium in a novel adrenal cell line developed using targeted tumorigenesis.
    BioFactors (Oxford, England), 2001, Volume: 14, Issue:1-4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Aldosterone; Animals; Cell Line; Cell Transformation, Neoplastic; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Phosphoproteins; Progesterone; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Transcription, Genetic

2001
Regulated expression of sterol carrier protein 2 in the ovary: a key role for cyclic AMP.
    Biochemistry, 1991, Nov-26, Volume: 30, Issue:47

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Gene Expression Regulation; Genes, ras; Gonadotropins, Equine; Granulosa Cells; Kinetics; Ovary; Plant Proteins; Rats; Rats, Inbred Strains; RNA, Messenger; Simian virus 40; Sterols

1991
8-Chloro-cAMP inhibits transforming growth factor alpha transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation.
    The Journal of biological chemistry, 1990, Jan-15, Volume: 265, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Isoenzymes; Mammary Glands, Animal; Mice; Protein Kinases; Radioimmunoassay; Radioligand Assay; RNA; RNA, Messenger; Transforming Growth Factors

1990
The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:17

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chromatin; Colforsin; Cyclic AMP; DNA; DNA, Neoplasm; Phenotype

1990
Confocal microscopy of genome exposure in normal, cancer, and reverse-transformed cells.
    Somatic cell and molecular genetics, 1991, Volume: 17, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Nucleolus; Cell Nucleus; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; Deoxyribonuclease I; DNA; DNA, Neoplasm; Fibroblasts; Genome; Microscopy, Fluorescence; Phenotype; Tumor Cells, Cultured

1991
Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphate.
    Molecular and cellular biology, 1990, Volume: 10, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diglycerides; Dinoprostone; Dogs; Genes, ras; GTP-Binding Proteins; Guanine Nucleotides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Oncogene Protein p21(ras); Phospholipids; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella

1990
Thyrotropin modulates low density lipoprotein binding activity in FRTL-5 thyroid cells.
    The Journal of biological chemistry, 1990, Nov-05, Volume: 265, Issue:31

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Dactinomycin; Down-Regulation; Genes, ras; Kinetics; Lipoproteins, LDL; Rats; Receptors, LDL; Thyroid Gland; Thyrotropin; Time Factors

1990
Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium Channel Blockers; Cell Transformation, Neoplastic; Chick Embryo; Gene Products, gag; Isoquinolines; Kinetics; Oncogene Protein pp60(v-src); Oncogenes; Phorbol Esters; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Retroviridae Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Transcription, Genetic

1989
Possible involvement of normal p21 H-ras in the insulin/insulinlike growth factor 1 signal transduction pathway.
    Molecular and cellular biology, 1989, Volume: 9, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclic AMP; DNA Replication; Gene Expression; Growth Substances; Insulin; Insulin-Like Growth Factor I; Oncogene Protein p21(ras); Phosphorylation; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Signal Transduction

1989