8-bromo cyclic adenosine monophosphate and Benign Neoplasms

8-bromo cyclic adenosine monophosphate has been researched along with Benign Neoplasms in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (60.00)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahn, YH; Cho, YJ; Choi, KY; Hong, SH; Kim, JS1
Borghi, MO; Calebiro, D; de Filippis, T; Grassi, ES; Lucchi, S; Persani, L1
Ahn, HW; Ahn, YH; Cho, YJ; Choi, KY; Hong, SH1
Becker, KG; Cheadle, C; Cho, YS; Cho-Chung, YS; Kim, MK; Lee, YN; Neary, C; Nesterova, M; Park, YG; Srivastava, R1
Cho-Chung, YS; Nesterova, MV1
Baksi, K; Banerjee, DK; Martínez, JA; Tavárez-Pagán, JJ1
Bronte, V1
Budillon, A; Cho-Chung, YS; Clair, T; Nesterova, M; Pepe, S1
Bell, PB; Bosanquet, AG; Burlton, AR; Harris, AL1
Harris, AL; Long, L; Mawer, EB; O'Byrne, KJ; Salisbury, AJ; Saunders, MP; Talbot, DC; Whitehouse, RM1
Ciardiello, F; Tortora, G1
Abbruzzese, A; Barbarulo, D; Budillon, A; Caraglia, M; Di Gennaro, E; Marra, M; Tagliaferri, P1
Braybrooke, JP; Dowsett, M; Ganesan, TS; Harris, AL; Long, L; O'Byrne, KJ; Propper, DJ; Salisbury, AJ; Saunders, MP; Talbot, DC; Taylor, M1
Cho-Chung, YS1
Greiner, JW; Guadagni, F; Roselli, M; Schlom, J1

Reviews

6 review(s) available for 8-bromo cyclic adenosine monophosphate and Benign Neoplasms

ArticleYear
Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy.
    Annals of the New York Academy of Sciences, 2002, Volume: 968

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antineoplastic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Neoplasms; Oligodeoxyribonucleotides, Antisense; Oligonucleotide Array Sequence Analysis; Protein Subunits; Second Messenger Systems; Signal Transduction; Transcription Factors

2002
Tumor reversion: protein kinase A isozyme switching.
    Annals of the New York Academy of Sciences, 2005, Volume: 1058

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Phenotype; Protein Isoforms

2005
cAMP-dependent protein kinase: role in normal and malignant growth.
    Critical reviews in oncology/hematology, 1995, Volume: 21, Issue:1-3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Binding Sites; Cell Cycle; Cell Differentiation; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Genetic Vectors; Growth Inhibitors; Isoenzymes; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms; Oligonucleotides, Antisense; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Receptors, Cell Surface; Signal Transduction; Subcellular Fractions; Tumor Cells, Cultured

1995
Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinases; ErbB Receptors; Genes, ras; Humans; Neoplasms; Transforming Growth Factor alpha

1998
Suppression of malignancy targeting cyclic AMP signal transducing proteins.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; Cells; Cyclic AMP; Female; Humans; Macromolecular Substances; Neoplasm Metastasis; Neoplasms; Oligonucleotides, Antisense; Protein Kinases; Receptors, Cyclic AMP; RNA, Messenger; Signal Transduction

1992
Regulation of human tumor antigen expression by biological response modifiers (BRMs).
    Annali dell'Istituto superiore di sanita, 1991, Volume: 27, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Immunologic Factors; Interferon-gamma; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Recombinant Proteins; Transplantation, Heterologous; Tumor Cells, Cultured

1991

Trials

2 trial(s) available for 8-bromo cyclic adenosine monophosphate and Benign Neoplasms

ArticleYear
A novel cyclic adenosine monophosphate analog induces hypercalcemia via production of 1,25-dihydroxyvitamin D in patients with solid tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:12

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Adult; Antineoplastic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Feasibility Studies; Humans; Hypercalcemia; Neoplasms; Parathyroid Hormone; Vitamin D

1997
Phase I study of the novel cyclic AMP (cAMP) analogue 8-chloro-cAMP in patients with cancer: toxicity, hormonal, and immunological effects.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Aged; Antineoplastic Agents; Cytokines; Female; Hormones; Humans; Hypercalcemia; Kidney; Liver; Lymphocyte Subsets; Male; Middle Aged; Nausea; Neoplasms; Treatment Outcome; Vomiting

1999

Other Studies

7 other study(ies) available for 8-bromo cyclic adenosine monophosphate and Benign Neoplasms

ArticleYear
SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Kinase; Cell Division; Cell Line, Tumor; Humans; Mass Spectrometry; Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Signal Transduction

2015
8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Kinase; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Subunits; Proto-Oncogene Proteins c-akt; Signal Transduction

2011
Involvement of Akt2/protein kinase B β (PKBβ) in the 8-Cl-cAMP-induced cancer cell growth inhibition.
    Journal of cellular physiology, 2013, Volume: 228, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; HeLa Cells; Humans; MCF-7 Cells; Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Ribonucleotides

2013
Unique structural motif supports mannosylphospho dolichol synthase: an important angiogenesis regulator.
    Current drug targets, 2008, Volume: 9, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apoptosis; Cell Proliferation; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Endothelial Cells; Flow Cytometry; G1 Phase; Gene Expression Regulation; Humans; Lipopolysaccharides; Mannosyltransferases; Neoplasms; Neovascularization, Pathologic; Phosphorylation

2008
Molecular genetics of cancer. Gene therapy and other novel therapeutic approaches.
    Cancer, 1995, Nov-15, Volume: 76, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CD40 Antigens; Genetic Therapy; Humans; Neoplasms

1995
Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP.
    British journal of cancer, 1997, Volume: 76, Issue:4

    Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Drug Evaluation; Drug Resistance; Humans; Neoplasms

1997
Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP.
    FEBS letters, 1999, Mar-26, Volume: 447, Issue:2-3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Neoplasms; Signal Transduction; Tumor Cells, Cultured; Ubiquitins

1999