Compounds > 8-aminoquinoline
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8-aminoquinoline and Malaria, Falciparum

8-aminoquinoline has been researched along with Malaria, Falciparum in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Azhari, A; Blake, LD; Kemp, MT; Kyle, DE; Larsen, RW; Manetsch, R; McGaha, TW; McQueen, A; Namelikonda, N1
Alano, P; Baker, DA; Bhatia, SN; Biagini, GA; Camarda, G; Jirawatcharadech, P; Leung, S; March, S; Miller, AB; O'Neill, PM; Paine, MJI; Priestley, RS; Saif, A; Ward, SA; Wong, MHL1
Auburn, S; Baird, K; Bancone, G; Cheng, Q; Domingo, G; Espino, F; Green, J; Howes, R; McCarthy, J; Ménard, D; Moyes, C; Price, R; Shanks, D; Vestergaard, LS; von Seidlein, L; Winasti-Satyahraha, A; Yeung, S1
Abdul-Ghani, R; Beier, JC1
Iyer, PS; Kannan, M; Khan, FR; Raichurkar, AV1
Kaewpruk, N; Mungthin, M; Sitthichot, N; Suwandittakul, N; Tan-ariya, P; Ward, SA1
Chandra, S; Kumari, M; Subbarao, N; Tiwari, N1
Sullivan, DJ1
Brueckner, RP; Coster, T; Schuster, BG; Shmuklarsky, M; Wesche, DL1

Reviews

3 review(s) available for 8-aminoquinoline and Malaria, Falciparum

ArticleYear
Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report.
    Malaria journal, 2013, Mar-27, Volume: 12

    Topics: Aminoquinolines; Clinical Laboratory Techniques; Drug-Related Side Effects and Adverse Reactions; Glucosephosphate Dehydrogenase Deficiency; Humans; Korea; Malaria, Falciparum; Malaria, Vivax

2013
Strategic use of antimalarial drugs that block falciparum malaria parasite transmission to mosquitoes to achieve local malaria elimination.
    Parasitology research, 2014, Volume: 113, Issue:10

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Culicidae; Disease Eradication; Drug Resistance; Humans; Insect Vectors; Malaria, Falciparum; Plasmodium falciparum

2014
Plasmodium drug targets outside the genetic control of the parasite.
    Current pharmaceutical design, 2013, Volume: 19, Issue:2

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; DNA, Protozoan; Drug Design; Drug Resistance; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum

2013

Trials

1 trial(s) available for 8-aminoquinoline and Malaria, Falciparum

ArticleYear
Prophylaxis of Plasmodium falciparum infection in a human challenge model with WR 238605, a new 8-aminoquinoline antimalarial.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:5

    Topics: Adult; Aminoquinolines; Animals; Antimalarials; Double-Blind Method; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum

1998

Other Studies

5 other study(ies) available for 8-aminoquinoline and Malaria, Falciparum

ArticleYear
Synthesis, characterization, and cellular localization of a fluorescent probe of the antimalarial 8-aminoquinoline primaquine.
    Bioorganic & medicinal chemistry letters, 2017, 10-15, Volume: 27, Issue:20

    Topics: Aminoquinolines; Antimalarials; Erythrocytes; Fluorescent Dyes; Hep G2 Cells; Humans; Life Cycle Stages; Malaria, Falciparum; Microscopy, Fluorescence; Plasmodium falciparum; Primaquine

2017
Antimalarial activity of primaquine operates via a two-step biochemical relay.
    Nature communications, 2019, 07-19, Volume: 10, Issue:1

    Topics: Aminoquinolines; Antimalarials; Bone Marrow; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Liver; Malaria, Falciparum; NADP; Pharmacokinetics; Plasmodium falciparum; Primaquine

2019
Synthesis and in vitro evaluation of novel 8-aminoquinoline-pyrazolopyrimidine hybrids as potent antimalarial agents.
    Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5

    Topics: Aminoquinolines; Antimalarials; Humans; Malaria, Falciparum; Molecular Docking Simulation; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Pyrimidines; Structure-Activity Relationship

2015
PFMDR1 POLYMORPHISMS INFLUENCE ON IN VITRO SENSITIVITY OF THAI PLASMODIUM FALCIPARUM ISOLATES TO PRIMAQUINE, SITAMAQUINE AND TAFENOQUINE.
    The Southeast Asian journal of tropical medicine and public health, 2016, Volume: 47, Issue:3

    Topics: Aminoquinolines; Antimalarials; Humans; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Primaquine; Thailand

2016
3D QSAR, pharmacophore and molecular docking studies of known inhibitors and designing of novel inhibitors for M18 aspartyl aminopeptidase of Plasmodium falciparum.
    BMC structural biology, 2016, 08-17, Volume: 16

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Design; Glutamyl Aminopeptidase; Humans; Malaria, Falciparum; Molecular Docking Simulation; Plasmodium falciparum; Quantitative Structure-Activity Relationship

2016