8-11-14-eicosatrienoic-acid and Cell-Transformation--Viral

8-11-14-eicosatrienoic-acid has been researched along with Cell-Transformation--Viral* in 1 studies

Other Studies

1 other study(ies) available for 8-11-14-eicosatrienoic-acid and Cell-Transformation--Viral

ArticleYear
Endogenous synthesis of prostaglandins E1 and I2 in 3T3 fibroblasts transformed by polyoma virus. Effects on adenosine 3':5'-monophosphate production.
    Prostaglandins, 1980, Volume: 19, Issue:1

    Prostaglandins (PG)E1, E2 and I2 were produced by polyoma virus transformed (py) 3T3 fibroblasts. The levels of PGE1, PGE2 and 6-keto-PGF1 alpha (degradation product of PGI2) were 22.7, 225 and 33.2 ng/ml medium, respectively, 72 h after medium change. The stimulatory potencies of exogenous PGE1, PGE2 and PGI2 on adenosine 3':5'-monophosphate (cyclic AMP) formation were similar. Therefore, the prostaglandin mediated increase in cyclic AMP levels observed during growth of these cells (Claesson, H.-E., Lindgren, J.A. and Hammarström, S. (1977) Eur. J. Biochem. 74, 13) is largely (greater than 80%) mediated by PGE2 and to lesser extents by PGE1 and PGI2.

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Cell Transformation, Viral; Cyclic AMP; Epoprostenol; Fibroblasts; Polyomavirus; Prostaglandins; Prostaglandins E

1980