8-(trifluoromethyl)-1-2-3-4-5-benzopentathiepin-6-amine and Retinal-Diseases

8-(trifluoromethyl)-1-2-3-4-5-benzopentathiepin-6-amine has been researched along with Retinal-Diseases* in 1 studies

Other Studies

1 other study(ies) available for 8-(trifluoromethyl)-1-2-3-4-5-benzopentathiepin-6-amine and Retinal-Diseases

ArticleYear
Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development.
    International journal of molecular sciences, 2020, Jul-22, Volume: 21, Issue:15

    Tyrosine phosphatase STEP (striatal-enriched tyrosine protein phosphatase) is a brain-specific protein phosphatase and is involved in the pathogenesis of many neurodegenerative diseases. Here, we examined the impact of STEP on the development of age-related macular degeneration (AMD)-like pathology in senescence-accelerated OXYS rats. Using OXYS and Wistar rats (control), we for the first time demonstrated age-dependent changes in

    Topics: Aging; Animals; Apoptosis; Benzothiepins; Brain-Derived Neurotrophic Factor; Cellular Senescence; Gene Expression Regulation; Macular Degeneration; Male; Nerve Growth Factor; Neuroglia; Neurons; Protein Tyrosine Phosphatases, Non-Receptor; Rats; Rats, Wistar; Retina; Retinal Diseases

2020