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8-(4-sulfophenyl)theophylline and Hyperemia

8-(4-sulfophenyl)theophylline has been researched along with Hyperemia in 6 studies

8-(4-sulfophenyl)theophylline: adenosine antagonist

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
"We have previously demonstrated that adenosine-mediated H2O2 production and opening of ATP-sensitive K(+) (KATP) channels contributes to coronary reactive hyperemia."7.80Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts. ( Ledent, C; Mustafa, SJ; Teng, B; Tilley, S; Zhou, X, 2014)
"To investigate the role of endothelium-derived nitric oxide (EDNO) and adenosine in functional myocardial hyperemia, we examined the effect of NG-nitro-L-arginine (L-NNA) and 8-p-sulfophenyltheophylline (8-SPT) on coronary vasodilation in response to increased myocardial oxygen consumption in pentobarbital sodium-anesthetized dogs."7.69Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia. ( Haraoka, S; Maekawa, K; Obayashi, N; Saito, D; Uchida, S, 1994)
"The present study tested the hypothesis that adenosine is involved in mediating the hyperemic response of the newborn brain to hypoglycemia."7.68Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet. ( Gidday, JM; Gonzales, ER; Park, TS; Ruth, VJ, 1993)
"Ischemia was induced for 1 h in both eyes by elevation of intraocular pressure above systolic arterial pressure."5.29Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade. ( Roth, S, 1995)
"We have previously demonstrated that adenosine-mediated H2O2 production and opening of ATP-sensitive K(+) (KATP) channels contributes to coronary reactive hyperemia."3.80Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts. ( Ledent, C; Mustafa, SJ; Teng, B; Tilley, S; Zhou, X, 2014)
"To investigate the role of endothelium-derived nitric oxide (EDNO) and adenosine in functional myocardial hyperemia, we examined the effect of NG-nitro-L-arginine (L-NNA) and 8-p-sulfophenyltheophylline (8-SPT) on coronary vasodilation in response to increased myocardial oxygen consumption in pentobarbital sodium-anesthetized dogs."3.69Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia. ( Haraoka, S; Maekawa, K; Obayashi, N; Saito, D; Uchida, S, 1994)
"The present study tested the hypothesis that adenosine is involved in mediating the hyperemic response of the newborn brain to hypoglycemia."3.68Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet. ( Gidday, JM; Gonzales, ER; Park, TS; Ruth, VJ, 1993)
"Ischemia was induced for 1 h in both eyes by elevation of intraocular pressure above systolic arterial pressure."1.29Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade. ( Roth, S, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, X1
Teng, B1
Tilley, S1
Ledent, C1
Mustafa, SJ1
Ray, CJ1
Marshall, JM1
Roth, S2
Maekawa, K1
Saito, D1
Obayashi, N1
Uchida, S1
Haraoka, S1
Ruth, VJ1
Park, TS1
Gonzales, ER1
Gidday, JM1
Ostwald, P1
Park, SS1
Toledano, AY1

Other Studies

6 other studies available for 8-(4-sulfophenyl)theophylline and Hyperemia

ArticleYear
Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts.
    American journal of physiology. Heart and circulatory physiology, 2014, Oct-01, Volume: 307, Issue:7

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Coronary Circulation; Free Radical Scavengers

2014
Elucidation in the rat of the role of adenosine and A2A-receptors in the hyperaemia of twitch and tetanic contractions.
    The Journal of physiology, 2009, Apr-01, Volume: 587, Issue:Pt 7

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Carbon Dioxide; Electric Stim

2009
Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade.
    Current eye research, 1995, Volume: 14, Issue:4

    Topics: Adenosine; Animals; Blood Flow Velocity; Cats; Choroid; Hemodynamics; Hyperemia; Ischemia; Microsphe

1995
Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: Adenosine; Animals; Arginine; Coronary Circulation; Dogs; Female; Hemodynamics; Hyperemia; Male; Nit

1994
Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Adenosine; Animals; Animals, Newborn; Arterioles; Blood Glucose; Blood Pressure; Brain; Carbon Dioxi

1993
Adenosine receptor blockade and nitric oxide synthase inhibition in the retina: impact upon post-ischemic hyperemia and the electroretinogram.
    Vision research, 1997, Volume: 37, Issue:24

    Topics: Analysis of Variance; Animals; Arginine; Cats; Choroid; Electroretinography; Hyperemia; Ischemia; Mi

1997