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8-(4-sulfophenyl)theophylline and Cardiovascular Stroke

8-(4-sulfophenyl)theophylline has been researched along with Cardiovascular Stroke in 32 studies

8-(4-sulfophenyl)theophylline: adenosine antagonist

Research Excerpts

ExcerptRelevanceReference
" The present study examined whether or not cilostazol reduces the myocardial infarct size, and investigated its mechanism in a rabbit model of myocardial infarction."7.77Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels. ( Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y, 2011)
" The present study examined whether or not cilostazol reduces the myocardial infarct size, and investigated its mechanism in a rabbit model of myocardial infarction."3.77Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels. ( Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y, 2011)
"Adenosine concentration was significantly increased in IPC effluent (2."1.40Remote cardioprotection by transfer of coronary effluent from ischemic preconditioned rabbit heart preserves mitochondrial integrity and function via adenosine receptor activation. ( Caldarone, CA; Callahan, J; Fu, YY; Kato, H; Leung, CH; Nielsen, JM; Redington, AN; Tropak, MB; Wang, L, 2014)
"Tyramine (Tyr) was intravenously administered before 30 min ischaemia in the absence or presence of bunazosin (BN, alpha1-receptor blocker) and staurosporine (ST), a protein kinase C inhibitor, respectively."1.33Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits. ( Baba, K; Fujiwara, H; Kariya, T; Kawai, T; Minatoguchi, S; Takahashi, M; Takemura, G; Uno, Y; Zhang, C, 2005)
"(3) Treatment with acadesine (2."1.29Acadesine extends the window of protection afforded by ischaemic preconditioning. ( Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM, 1994)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (59.38)18.2507
2000's10 (31.25)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leung, CH1
Wang, L1
Nielsen, JM1
Tropak, MB1
Fu, YY1
Kato, H1
Callahan, J1
Redington, AN1
Caldarone, CA1
Paiva, M1
Riksen, NP1
Davidson, SM1
Hausenloy, DJ1
Monteiro, P1
Gonçalves, L1
Providência, L1
Rongen, GA1
Smits, P1
Mocanu, MM1
Yellon, DM3
Vessey, DA1
Li, L1
Honbo, N1
Karliner, JS1
Bai, Y1
Murakami, H1
Iwasa, M1
Sumi, S1
Yamada, Y1
Ushikoshi, H1
Aoyama, T1
Nishigaki, K1
Takemura, G2
Uno, B1
Minatoguchi, S2
Darbera, L1
Chenoune, M1
Lidouren, F1
Ghaleh, B1
Cohen, MV7
Downey, JM9
Berdeaux, A1
Tissier, R1
Asanuma, H3
Sanada, S2
Ogai, A2
Minamino, T4
Takashima, S3
Asakura, M1
Ogita, H1
Shinozaki, Y3
Mori, H3
Node, K3
Tomoike, H2
Hori, M3
Kitakaze, M4
Okuda, H1
Fujita, M2
Hirata, A2
Kim, J2
Asano, Y1
Kitamura, S1
Baba, K1
Zhang, C1
Kariya, T1
Uno, Y1
Kawai, T1
Takahashi, M1
Fujiwara, H1
Kin, H1
Zatta, AJ1
Lofye, MT1
Amerson, BS1
Halkos, ME1
Kerendi, F1
Zhao, ZQ3
Guyton, RA1
Headrick, JP1
Vinten-Johansen, J4
Solenkova, NV1
Solodushko, V1
Wakeno, M1
Seguchi, O1
Okazaki, H1
Tsukamoto, O1
Okada, K1
Komamura, K1
Mochizuki, N1
Armstrong, S1
Ganote, CE1
Bugge, E1
Ytrehus, K1
Williams, MW1
Sato, H1
Hudspeth, DA1
McGee, DS2
Van Wylen, DG1
Woolfson, RG1
Patel, VC2
Neild, GH1
Offstad, J1
Kirkebøen, KA1
Ilebekk, A2
Downing, SE1
Liu, GS2
Richards, SC1
Olsson, RA2
Mullane, K1
Walsh, RS3
Tsuchida, A3
Daly, JJ1
Thornton, JD1
Baxter, GF1
Marber, MS1
Nakanishi, K1
Tan, P1
Yang, XM2
Burckhartt, B1
Mullane, KM1
Goto, M2
Wang, P1
Gallagher, KP1
Funaya, H1
Gysembergh, A1
Margonari, H1
Loufoua, J1
Ovize, A1
André-Fouët, X1
Minaire, Y1
Ovize, M1
Miura, T2
Kawamura, S1
Sakamoto, J1
Matsuzaki, M1
Shimamoto, K1
Grund, F1
Sommerschild, HT1
Lyberg, T1
Kirkeboen, KA1
Liem, DA2
van den Doel, MA1
de Zeeuw, S1
Verdouw, PD2
Duncker, DJ2
Ploeg, H1
Kazim, S1
Toombs, CF1
McGee, S1
Johnston, WE1
Thornton, J1
Van Winkle, DM1
Stanley, AW1

Other Studies

32 other studies available for 8-(4-sulfophenyl)theophylline and Cardiovascular Stroke

ArticleYear
Remote cardioprotection by transfer of coronary effluent from ischemic preconditioned rabbit heart preserves mitochondrial integrity and function via adenosine receptor activation.
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:1

    Topics: Adenosine; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Mitochondria

2014
Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5

    Topics: Adenosine; Animals; Biological Transport; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin;

2009
Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4

    Topics: Adenosine; Animals; Animals, Newborn; Cells, Cultured; In Vitro Techniques; Ischemic Preconditioning

2009
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:10

    Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Eva

2011
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial In

2012
Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:4

    Topics: 2-Aminoadipic Acid; Adenosine; Animals; Cardiotonic Agents; Dogs; Methotrexate; Myocardial Infarctio

2004
Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.
    Circulation, 2004, Oct-12, Volume: 110, Issue:15

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Androstadienes; Animals; Cardiotonic Agents; Chromones; Cor

2004
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adrenergic alpha-1 Rec

2005
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
    Cardiovascular research, 2005, Jul-01, Volume: 67, Issue:1

    Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Puri

2005
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1

    Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Androstadienes; An

2006
Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats.
    Circulation, 2006, Oct-31, Volume: 114, Issue:18

    Topics: 2-Chloroadenosine; Acetamides; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; An

2006
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocar

1994
Ischaemic preconditioning is protein kinase C dependent but not through stimulation of alpha adrenergic or adenosine receptors in the isolated rat heart.
    Cardiovascular research, 1995, Volume: 29, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; In Vitro Techniques; Male; Myocardial Infarction; Myocardi

1995
Acadesine reduces myocardial infarct size by an adenosine mediated mechanism.
    Cardiovascular research, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Extracellular Space; In Vitro

1995
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfu

1995
ATP gated potassium channels in acute myocardial hibernation and reperfusion.
    Cardiovascular research, 1994, Volume: 28, Issue:6

    Topics: Adenosine Triphosphate; Animals; Glyburide; Ion Channel Gating; Myocardial Infarction; Myocardial Re

1994
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarctio

1994
Ketamine-xylazine anaesthesia permits a KATP channel antagonist to attenuate preconditioning in rabbit myocardium.
    Cardiovascular research, 1994, Volume: 28, Issue:9

    Topics: Animals; Glyburide; Guanidines; Ketamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Pi

1994
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning.
    Circulation, 1994, Volume: 90, Issue:6

    Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardia

1994
A1 receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia.
    Cardiovascular research, 1994, Volume: 28, Issue:2

    Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Myocardial Infarction; Myocardial Ische

1994
Acadesine extends the window of protection afforded by ischaemic preconditioning.
    Cardiovascular research, 1994, Volume: 28, Issue:3

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Isch

1994
Hypoxia preconditions rabbit myocardium via adenosine and catecholamine release.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:8

    Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Catecholamines; Heart; Hemodynamics; Hypoxia; In V

1995
Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heart.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Coronary Vessels; Dioxoles; Endothelin Receptor Antagonist

1996
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs;

1997
Attenuation of S-T segment elevation during repetitive coronary occlusions truly reflects the protection of ischemic preconditioning and is not an epiphenomenon.
    Basic research in cardiology, 1997, Volume: 92, Issue:6

    Topics: Animals; Coronary Disease; Electrocardiography; Hemodynamics; Injections, Intravenous; Ischemic Prec

1997
Stretch-induced protection shares a common mechanism with ischemic preconditioning in rabbit heart.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Animals; Coronary Circulation; Elasticity; Glyburide; Heart; Hematocrit; Hemodynamics; Ischemic Prec

1998
Effect of protein kinase C inhibitors on cardioprotection by ischemic preconditioning depends on the number of preconditioning episodes.
    Cardiovascular research, 1998, Volume: 37, Issue:3

    Topics: Animals; Cell Membrane; Cytosol; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Myoc

1998
Microembolization in pigs: effects on coronary blood flow and myocardial ischemic tolerance.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Embolism; Female; Ischemic Pr

1999
Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors.
    Cardiovascular research, 2001, Volume: 51, Issue:4

    Topics: Acetamides; Adenosine; Analysis of Variance; Animals; Cryoprotective Agents; Dihydropyridines; Hista

2001
Sites of action of adenosine in interorgan preconditioning of the heart.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Coronary Vessels; Ganglionic Blockers; Heart Rate; Hexamethonium

2002
Myocardial protective effects of adenosine. Infarct size reduction with pretreatment and continued receptor stimulation during ischemia.
    Circulation, 1992, Volume: 86, Issue:3

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Heart; Hemodynamics; Male; Methods; Myoc

1992
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
    Circulation, 1991, Volume: 84, Issue:1

    Topics: Adenosine; Animals; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Purin

1991