Page last updated: 2024-10-21

8-(4-sulfophenyl)theophylline and Aging

8-(4-sulfophenyl)theophylline has been researched along with Aging in 2 studies

8-(4-sulfophenyl)theophylline: adenosine antagonist

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matherne, GP1
Berr, SS1
Headrick, JP1
Snyder, DL1
Wang, W1
Pelleg, A1
Friedman, E1
Horwitz, J1
Roberts, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Attenuation of Myocardial Dysfunction by N-Acetylcysteine in Infants Undergoing Arterial Switch Procedure[NCT00374088]Phase 221 participants (Actual)Interventional2005-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Max Creatinine

Maximum serum creatinine over first 3 days postoperative. (NCT00374088)
Timeframe: 72 hours

Interventionmg/dL (Mean)
Placebo0.99
N-acetylcysteine0.74

Maximum Decline in Measured Cardiac Output

Serial cardiac output was measured by thermodilution. The outcome of maximum decline in indexed cardiac output from 1 hour postoperative to lowest output within 24 hours postoperative was then calculated and compared between NAC and placebo groups. (NCT00374088)
Timeframe: 24 hours

InterventionL/min/m2 (Mean)
Placebo0.68
N-acetylcysteine0.29

Urine Output

Total urine output over the first 24 hours postoperative (NCT00374088)
Timeframe: 24 hours

InterventionmL (Mean)
Placebo96
N-acetylcysteine176

Other Studies

2 other studies available for 8-(4-sulfophenyl)theophylline and Aging

ArticleYear
Integration of vascular, contractile and metabolic responses to hypoxia: effects of maturation and adenosine.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2

    Topics: Adenosine; Aging; Animals; Coronary Circulation; Coronary Vessels; Energy Metabolism; Heart; Hemodyn

1996
Effect of aging on A1-adenosine receptor-mediated inhibition of norepinephrine release in the rat heart.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Heart; Male; Myocardium; Norepinephrine; Rats; Rats,

1998