7-nitroindazole has been researched along with Reperfusion Injury in 19 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Global cerebral ischemia/reperfusion promoted the binding between neuronal nitric oxide synthase (nNOS) and postsynaptic density protein 95 that has been reported to activate nNOS, and GSNO inhibited the post-ischemic nNOS activation and NO release." | 1.39 | Neuroprotection of S-nitrosoglutathione against ischemic injury by down-regulating Fas S-nitrosylation and downstream signaling. ( Hou, XY; Wu, SL; Yan, JZ; Yin, XH; Zhang, GY, 2013) |
| "Transient brain ischemia was induced by the four-vessel occlusion in Sprague-Dawley rats." | 1.35 | S-nitrosylation of PTEN Invovled in ischemic brain injury in rat hippocampal CA1 region. ( Pei, DS; Song, YJ; Sun, YF, 2009) |
| "Reperfusion injury is one of the factors that unfavorably affects stroke outcome and shortens the window of opportunity for thrombolysis." | 1.31 | Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia. ( Bolay, H; Dalkara, T; Gürsoy-Ozdemir, Y; Saribaş, O, 2000) |
| "Transient local anoxia of the cochlea was induced in albino guinea pigs for 15, 30, or 60 minutes by transiently compressing the labyrinthine artery through a skull base approach." | 1.31 | Effect of 7-nitroindazole upon cochlear dysfunction induced by transient local anoxia. ( Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Takahashi, K; Wada, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, LM | 1 |
| Zhang, TY | 1 |
| Yin, XH | 2 |
| Yang, Q | 1 |
| Lu, F | 1 |
| Yan, JZ | 2 |
| Li, C | 3 |
| Hou, XY | 1 |
| Wu, SL | 1 |
| Zhang, GY | 3 |
| Rusai, K | 1 |
| Fekete, A | 1 |
| Szebeni, B | 1 |
| Vannay, A | 1 |
| Bokodi, G | 1 |
| Müller, V | 1 |
| Viklicky, O | 1 |
| Bloudickova, S | 1 |
| Rajnoch, J | 1 |
| Heemann, U | 1 |
| Reusz, G | 1 |
| Szabó, A | 1 |
| Tulassay, T | 1 |
| Szabó, AJ | 1 |
| Pei, DS | 1 |
| Sun, YF | 1 |
| Song, YJ | 1 |
| Liu, K | 2 |
| Li, Q | 1 |
| Zhang, L | 1 |
| Zheng, X | 2 |
| Yang, Y | 1 |
| Tang, LJ | 1 |
| Hu, SQ | 1 |
| Wu, YP | 2 |
| Zong, YY | 1 |
| Sun, CC | 1 |
| Zhang, F | 1 |
| Feng, JJ | 1 |
| Bémeur, C | 1 |
| Ste-Marie, L | 1 |
| Desjardins, P | 1 |
| Butterworth, RF | 1 |
| Vachon, L | 1 |
| Montgomery, J | 1 |
| Hazell, AS | 1 |
| Viñas, JL | 1 |
| Sola, A | 1 |
| Genescà, M | 1 |
| Alfaro, V | 1 |
| Pí, F | 1 |
| Hotter, G | 1 |
| Dudley, RW | 1 |
| Danialou, G | 1 |
| Govindaraju, K | 1 |
| Lands, L | 1 |
| Eidelman, DE | 1 |
| Petrof, BJ | 1 |
| Li, X | 1 |
| Nemoto, M | 1 |
| Xu, Z | 1 |
| Yu, SW | 1 |
| Shimoji, M | 1 |
| Andrabi, SA | 1 |
| Haince, JF | 1 |
| Poirier, GG | 1 |
| Dawson, TM | 1 |
| Dawson, VL | 1 |
| Koehler, RC | 1 |
| Zhang, B | 1 |
| Knight, KR | 1 |
| Dowsing, B | 1 |
| Guida, E | 1 |
| Phan, LH | 1 |
| Hickey, MJ | 1 |
| Morrison, WA | 1 |
| Stewart, AG | 1 |
| Chalimoniuk, M | 1 |
| Strosznajder, J | 1 |
| Hirabayashi, H | 1 |
| Takizawa, S | 1 |
| Fukuyama, N | 1 |
| Nakazawa, H | 1 |
| Shinohara, Y | 1 |
| Jiang, MH | 1 |
| Kaku, T | 1 |
| Hada, J | 1 |
| Hayashi, Y | 1 |
| Gürsoy-Ozdemir, Y | 1 |
| Bolay, H | 1 |
| Saribaş, O | 1 |
| Dalkara, T | 1 |
| Tabuchi, K | 1 |
| Ito, Z | 1 |
| Wada, T | 1 |
| Takahashi, K | 1 |
| Hara, A | 1 |
| Kusakari, J | 1 |
| Pinard, E | 1 |
| Engrand, N | 1 |
| Seylaz, J | 1 |
19 other studies available for 7-nitroindazole and Reperfusion Injury
| Article | Year |
|---|---|
Denitrosylation of nNOS induced by cerebral ischemia-reperfusion contributes to nitrosylation of CaMKII and its inhibition of autophosphorylation in hippocampal CA1.
Topics: Animals; CA1 Region, Hippocampal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models | 2019 |
Neuroprotection of S-nitrosoglutathione against ischemic injury by down-regulating Fas S-nitrosylation and downstream signaling.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Caspase 3; Caspase 8; Caspase 9; Disease Models, A | 2013 |
Effect of inhibition of neuronal nitric oxide synthase and L-arginine supplementation on renal ischaemia-reperfusion injury and the renal nitric oxide system.
Topics: Animals; Arginine; Gene Expression Regulation, Enzymologic; Indazoles; Isoenzymes; Kidney; Male; Nit | 2008 |
S-nitrosylation of PTEN Invovled in ischemic brain injury in rat hippocampal CA1 region.
Topics: Animals; Blotting, Western; Brain Ischemia; Enzyme Inhibitors; Hippocampus; Immunoprecipitation; Ind | 2009 |
The dynamic detection of NO during stroke and reperfusion in vivo.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; Imines; Indazoles; Infusions, Intra | 2009 |
Real-time measurement of murine hippocampus NO levels in response to cerebral ischemia/reperfusion.
Topics: Amidines; Animals; Benzylamines; Brain Ischemia; Electrodes; Hippocampus; Indazoles; Nitric Oxide; N | 2011 |
S-nitrosylation of c-Src via NMDAR-nNOS module promotes c-Src activation and NR2A phosphorylation in cerebral ischemia/reperfusion.
Topics: Amino Acid Motifs; Animals; Apoptosis; Brain Ischemia; Cysteine; Dizocilpine Maleate; Enzyme Activat | 2012 |
Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation.
Topics: Active Transport, Cell Nucleus; Analysis of Variance; Animals; Apoptosis; Brain Ischemia; CA1 Region | 2012 |
Expression of superoxide dismutase in hyperglycemic focal cerebral ischemia in the rat.
Topics: Actins; Animals; Blood Glucose; Blotting, Western; Brain Ischemia; Dehydroascorbic Acid; Enzyme Inhi | 2004 |
NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion.
Topics: Amidines; Animals; Apoptosis; Benzylamines; Caspase 3; Caspases; Immunohistochemistry; Indazoles; Ki | 2006 |
Sarcolemmal damage in dystrophin deficiency is modulated by synergistic interactions between mechanical and oxidative/nitrosative stresses.
Topics: Animals; Dystrophin; Hindlimb; Indazoles; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skelet | 2006 |
Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus.
Topics: Animals; Apoptosis Inducing Factor; Behavior, Animal; Blotting, Western; Cell Nucleus; Enzyme Inhibi | 2007 |
Timing of administration of dexamethasone or the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester, is critical for effective treatment of ischaemia-reperfusion injury to rat skeletal muscle.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; DNA Probes; Enzyme Inhibitors; Indazoles; Isothiur | 1997 |
NMDA receptor-dependent nitric oxide and cGMP synthesis in brain hemispheres and cerebellum during reperfusion after transient forebrain ischemia in gerbils: effect of 7-Nitroindazole.
Topics: Animals; Brain Ischemia; Cerebellum; Cerebral Cortex; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibi | 1998 |
7-Nitroindazole attenuates nitrotyrosine formation in the early phase of cerebral ischemia-reperfusion in mice.
Topics: Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Indazoles; Male; Mice; Mice, Inbred C | 1999 |
7-Nitroindazole reduces nitric oxide concentration in rat hippocampus after transient forebrain ischemia.
Topics: Animals; Enzyme Inhibitors; Hippocampus; Hyperemia; Indazoles; Ischemic Attack, Transient; Male; Nit | 1999 |
Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Coloring Agents; Endothelium, Vascular; Enzyme Inhibitors; | 2000 |
Effect of 7-nitroindazole upon cochlear dysfunction induced by transient local anoxia.
Topics: Action Potentials; Animals; Cochlea; Differential Threshold; Enzyme Inhibitors; Guinea Pigs; Hypoxia | 2000 |
Dynamic cerebral microcirculatory changes in transient forebrain ischemia in rats: involvement of type I nitric oxide synthase.
Topics: Animals; Blood Flow Velocity; Carotid Artery, Common; Indazoles; Ischemic Attack, Transient; Male; M | 2000 |