7-nitroindazole has been researched along with Pregnancy in 8 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the effects of 7-nitroindazole (7-NI) and N-omega-nitro-L-arginine methyl ester (L-NAME) on the endogenous nitric oxide (NO) production in vivo, cerebral hemodynamics, and hippocampal lesions to investigate the different roles between endothelial NOS (eNOS) and neuronal NOS (nNOS) during kainic acid (KA)-induced seizures in newborn rabbits." | 7.71 | Different effects between 7-nitroindazole and L-NAME on cerebral hemodynamics and hippocampal lesions during kainic acid-induced seizures in newborn rabbits. ( Hoshika, A; Katoh, N; Matsuura, K; Miyajima, T; Ohyu, J; Takami, T; Takashima, S; Takei, Y, 2001) |
| "To determine the effect of prenatal lead exposure on brain monoaminergic systems, pregnant rats were given tap water containing 250 ppm lead acetate, for the duration of pregnancy, while tap water without lead (Pb(2+)) was substituted at birth." | 3.74 | Maternal lead exposure produces long-term enhancement of dopaminergic reactivity in rat offspring. ( Brus, R; Kostrzewa, RM; Nowak, P; Szczerbak, G, 2007) |
| "We examined the effects of 7-nitroindazole (7-NI) and N-omega-nitro-L-arginine methyl ester (L-NAME) on the endogenous nitric oxide (NO) production in vivo, cerebral hemodynamics, and hippocampal lesions to investigate the different roles between endothelial NOS (eNOS) and neuronal NOS (nNOS) during kainic acid (KA)-induced seizures in newborn rabbits." | 3.71 | Different effects between 7-nitroindazole and L-NAME on cerebral hemodynamics and hippocampal lesions during kainic acid-induced seizures in newborn rabbits. ( Hoshika, A; Katoh, N; Matsuura, K; Miyajima, T; Ohyu, J; Takami, T; Takashima, S; Takei, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kristek, F | 1 |
| Malekova, M | 1 |
| Ondrias, K | 1 |
| Cacanyiova, S | 1 |
| Yu, L | 1 |
| Derrick, M | 1 |
| Ji, H | 1 |
| Silverman, RB | 1 |
| Whitsett, J | 1 |
| Vásquez-Vivar, J | 1 |
| Tan, S | 1 |
| Groc, L | 1 |
| Jackson Hunter, T | 1 |
| Jiang, H | 1 |
| Bezin, L | 1 |
| Koubi, D | 1 |
| Corcoran, GB | 1 |
| Levine, RA | 1 |
| Szczerbak, G | 2 |
| Nowak, P | 2 |
| Kostrzewa, RM | 2 |
| Brus, R | 2 |
| Rajakumar, B | 1 |
| Flumerfelt, BA | 1 |
| Hrycyshyn, AW | 1 |
| Rajakumar, N | 1 |
| Nitka, D | 1 |
| Sitkiewicz, T | 1 |
| Takei, Y | 1 |
| Takashima, S | 1 |
| Ohyu, J | 1 |
| Matsuura, K | 1 |
| Katoh, N | 1 |
| Takami, T | 1 |
| Miyajima, T | 1 |
| Hoshika, A | 1 |
| Abram, SR | 1 |
| Alexander, BT | 1 |
| Bennett, WA | 1 |
| Granger, JP | 1 |
8 other studies available for 7-nitroindazole and Pregnancy
| Article | Year |
|---|---|
Blood pressure-independent hypotrophy of the heart, kidneys and conduit arteries after 7-nitroindazole administration to Wistar rats from the prenatal period to adulthood.
Topics: Animals; Aorta, Thoracic; Arterial Pressure; Body Weight; Carotid Arteries; Female; Heart; Indazoles | 2013 |
Neuronal nitric oxide synthase inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: comparison between JI-8 and 7-nitroindazole.
Topics: Animals; Animals, Newborn; Cerebral Palsy; Enzyme Inhibitors; Female; Fetus; Humans; Hypoxia-Ischemi | 2011 |
Nitric oxide synthase inhibition during development: effect on apoptotic death of dopamine neurons.
Topics: Animals; Animals, Newborn; Apoptosis; Body Weight; Dopamine; Enzyme Inhibitors; Female; Immunohistoc | 2002 |
Maternal lead exposure produces long-term enhancement of dopaminergic reactivity in rat offspring.
Topics: Amphetamine; Animals; Biogenic Amines; Central Nervous System Stimulants; Cerebral Cortex; Chromatog | 2007 |
Nitric oxide-containing neurons in long-term grafts in a rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Brain Tissue Transplantation; Choline; Disease Models, Animal; Female; In | 2007 |
Effect of prenatal lead exposure on nigrostriatal neurotransmission and hydroxyl radical formation in rat neostriatum: dopaminergic-nitrergic interaction.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Enzyme Inhibitors; Female; Hydroxyl Radical; Indazo | 2008 |
Different effects between 7-nitroindazole and L-NAME on cerebral hemodynamics and hippocampal lesions during kainic acid-induced seizures in newborn rabbits.
Topics: Animals; Animals, Newborn; Brain Chemistry; Cerebrovascular Circulation; Electroencephalography; Enz | 2001 |
Role of neuronal nitric oxide synthase in mediating renal hemodynamic changes during pregnancy.
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Indazoles; K | 2001 |