7-nitroindazole has been researched along with Neuralgia in 5 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a diabetic neuropathic pain model, pretreatment with celecoxib, L-NIL and 7-Ni, significantly increased the antihyperalgesic activity of both Met-F-AEA and AM 1241." | 1.42 | Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy. ( Bujalska-Zadrożny, M; de Cordé, A; Pawlik, K, 2015) |
| "IANX induced mechanical allodynia, which was diminished by intra-TG administration of selective nNOS inhibitors." | 1.39 | Nitric oxide signaling contributes to ectopic orofacial neuropathic pain. ( Echizenya, S; Honda, K; Ito, R; Iwata, K; Kaji, K; Lee, J; Ohara, K; Shinoda, M; Sugiyama, T; Takahashi, O; Urata, K; Watase, T, 2013) |
| "Compound 16 was shown to reverse thermal hyperalgesia in vivo in the Chung model of neuropathic pain." | 1.37 | Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain. ( Andrews, JS; Annedi, SC; Bunton, D; Christie, L; Lee, DK; Maddaford, SP; Mladenova, G; Porreca, F; Rakhit, S; Ramnauth, J; Zhang, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Annedi, SC | 1 |
| Maddaford, SP | 1 |
| Mladenova, G | 1 |
| Ramnauth, J | 1 |
| Rakhit, S | 1 |
| Andrews, JS | 1 |
| Lee, DK | 1 |
| Zhang, D | 1 |
| Porreca, F | 1 |
| Bunton, D | 1 |
| Christie, L | 1 |
| Sugiyama, T | 1 |
| Shinoda, M | 1 |
| Watase, T | 1 |
| Honda, K | 1 |
| Ito, R | 1 |
| Kaji, K | 1 |
| Urata, K | 1 |
| Lee, J | 1 |
| Ohara, K | 1 |
| Takahashi, O | 1 |
| Echizenya, S | 1 |
| Iwata, K | 1 |
| Bujalska-Zadrożny, M | 1 |
| de Cordé, A | 1 |
| Pawlik, K | 1 |
| Kunori, S | 1 |
| Matsumura, S | 1 |
| Okuda-Ashitaka, E | 1 |
| Katano, T | 1 |
| Audoly, LP | 1 |
| Urade, Y | 1 |
| Ito, S | 1 |
| Wang, W | 2 |
| Mei, XP | 1 |
| Wei, YY | 1 |
| Zhang, MM | 1 |
| Zhang, T | 1 |
| Xu, LX | 1 |
| Wu, SX | 1 |
| Li, YQ | 1 |
5 other studies available for 7-nitroindazole and Neuralgia
| Article | Year |
|---|---|
Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.
Topics: Analgesics; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Hot Temperature; Humans; Hyperalge | 2011 |
Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.
Topics: Animals; Arginine; Enzyme Inhibitors; Enzyme Precursors; Facial Pain; Hyperalgesia; Indazoles; Lip; | 2013 |
Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy.
Topics: Animals; Arachidonic Acids; Cannabinoids; Celecoxib; Cyclooxygenase Inhibitors; Diabetic Neuropathie | 2015 |
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.
Topics: Adenosine Triphosphate; Animals; Cell Movement; Cerebral Cortex; Cinnamates; Dinoprostone; Disease M | 2011 |
Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
Topics: Animals; Astrocytes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hype | 2011 |