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7-nitroindazole and Inflammation

7-nitroindazole has been researched along with Inflammation in 6 studies

7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated."5.317-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001)
"However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated."1.317-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Bortolanza, M1
Cavalcanti-Kiwiatkoski, R1
Padovan-Neto, FE1
da-Silva, CA1
Mitkovski, M1
Raisman-Vozari, R1
Del-Bel, E1
Tao, F1
Tao, YX1
Zhao, C1
Doré, S1
Liaw, WJ1
Raja, SN1
Johns, RA1
Kajekar, R1
Moore, PK1
Brain, SD1
Lawand, NB1
Willis, WD1
Westlund, KN1
Park, WS1
Chang, YS1
Lee, M1

Other Studies

6 other studies available for 7-nitroindazole and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease.
    Neurobiology of disease, 2015, Volume: 73

    Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Indazoles; Inflamma

2015
Differential roles of neuronal and endothelial nitric oxide synthases during carrageenan-induced inflammatory hyperalgesia.
    Neuroscience, 2004, Volume: 128, Issue:2

    Topics: Animals; Blotting, Western; Calcium; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitor

2004
Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism.
    Circulation research, 1995, Volume: 76, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Indazoles; Inflammation; Male;

1995
Blockade of joint inflammation and secondary hyperalgesia by L-NAME, a nitric oxide synthase inhibitor.
    Neuroreport, 1997, Mar-03, Volume: 8, Issue:4

    Topics: Analgesics; Animals; Arthritis; Carrageenan; Hyperalgesia; Indazoles; Inflammation; Injections, Intr

1997
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.
    Biology of the neonate, 2001, Volume: 80, Issue:1

    Topics: Animals; Animals, Newborn; Blood Glucose; Brain Diseases; Cerebral Cortex; Cerebrospinal Fluid; Dise

2001