Page last updated: 2024-10-21

7-nitroindazole and Hypercapnia

7-nitroindazole has been researched along with Hypercapnia in 14 studies

7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
" B6 mice continued to exhibit posthypoxic PB; however, the PB was characterized by longer cycle and apnea length."3.727-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains. ( Dick, TE; Han, F; Price, ER; Strohl, KP, 2003)
" Using intravital microscopy and a closed cranial window system in adult rats, we measured pial arteriolar diameters during normo- and hypercapnia, first in the absence and then in the presence of a neuronal NOS (nNOS) inhibitor [7-nitroindazole (7-NI)]."3.70Miconazole represses CO(2)-induced pial arteriolar dilation only under selected circumstances. ( Pelligrino, DA; Santizo, RA; Wang, Q, 1999)
"Hypercapnia was induced for 10 minutes by inhalation of 5% carbon dioxide with 21% oxygen and 74% nitrogen."1.32Role of nitric oxide in regulation of retinal blood flow during hypercapnia in cats. ( Mori, F; Nagaoka, T; Sakamoto, T; Sato, E; Takakusaki, K; Yoshida, A, 2003)
"Since chronic hypertension has been associated with impaired endothelial function, we designed a study to find out whether hypercapnic cerebral blood flow and its nitric oxide- and prostaglandin-sensitive component is reduced in spontaneously hypertensive rats (SHR) compared with normotensive controls."1.30Hypercapnic cerebral blood flow in spontaneously hypertensive rats. ( Casadei, B; Heinert, G; Paterson, DJ, 1998)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (71.43)18.2507
2000's4 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Price, ER1
Han, F1
Dick, TE1
Strohl, KP1
Sato, E1
Sakamoto, T1
Nagaoka, T1
Mori, F1
Takakusaki, K1
Yoshida, A1
Wang, Q3
Pelligrino, DA3
Baughman, VL1
Koenig, HM1
Albrecht, RF1
Iadecola, C1
Zhang, F1
Fabricius, M1
Rubin, I1
Bundgaard, M1
Lauritzen, M1
Smith, JJ1
Lee, JG1
Hudetz, AG2
Hillard, CJ1
Bosnjak, ZJ2
Kampine, JP2
Okamoto, H1
Roman, RJ1
Harada, M1
Fuse, A1
Tanaka, Y1
Bryan, RM1
Heinert, G2
Casadei, B1
Paterson, DJ2
Nye, PC1
Santizo, RA1
Rosenblum, WI1
Kontos, HA1
Wei, EP1
Zhang, Y1
Leffler, CW1

Other Studies

14 other studies available for 7-nitroindazole and Hypercapnia

ArticleYear
7-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:3

    Topics: Animals; Apnea; Carbon Dioxide; Enzyme Inhibitors; Hypercapnia; Hypoxia; Indazoles; Mice; Mice, Inbr

2003
Role of nitric oxide in regulation of retinal blood flow during hypercapnia in cats.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:11

    Topics: Animals; Blood Flow Velocity; Cats; Enzyme Inhibitors; Hypercapnia; Indazoles; Injections; Injection

2003
The role of neuronal nitric oxide synthase in regulation of cerebral blood flow in normocapnia and hypercapnia in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Carbon Dioxide; Cerebrovascular Circulation; Hypercapnia; Indaz

1995
Permissive and obligatory roles of NO in cerebrovascular responses to hypercapnia and acetylcholine.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Cerebrovascular Circulation; Dose-Re

1996
NOS activity in brain and endothelium: relation to hypercapnic rise of cerebral blood flow in rats.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: Acetylcholine; Administration, Topical; Animals; Aorta; Brain; Carbon Dioxide; Cerebrovascular Circu

1996
The role of nitric oxide in the cerebrovascular response to hypercapnia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:2

    Topics: Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Enzyme Inhibitors; Hypercapnia; Indazol

1997
Neuronal NOS-derived NO plays permissive role in cerebral blood flow response to hypercapnia.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2

    Topics: Animals; Cerebrovascular Circulation; Enzyme Inhibitors; Epoprostenol; Hypercapnia; Iloprost; Indazo

1997
Measurement of nitric oxide in the rat cerebral cortex during hypercapnoea.
    Neuroreport, 1997, Mar-03, Volume: 8, Issue:4

    Topics: Animals; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Enzyme Inhibitors; Hypercapni

1997
Calcium-dependent and ATP-sensitive potassium channels and the 'permissive' function of cyclic GMP in hypercapnia-induced pial arteriolar relaxation.
    Brain research, 1998, May-18, Volume: 793, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Blood Pressure; Calcium; Carbon Dioxide; Cerebral A

1998
Hypercapnic cerebral blood flow in spontaneously hypertensive rats.
    Journal of hypertension, 1998, Volume: 16, Issue:10

    Topics: Animals; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulation; Enzyme Inhibitors; Hyper

1998
Nitric oxide and prostaglandin pathways interact in the regulation of hypercapnic cerebral vasodilatation.
    Acta physiologica Scandinavica, 1999, Volume: 166, Issue:3

    Topics: Animals; Antihypertensive Agents; Cerebrovascular Circulation; Enzyme Inhibitors; Epoprostenol; Hype

1999
Miconazole represses CO(2)-induced pial arteriolar dilation only under selected circumstances.
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Animals; Arterioles; Carbon Dioxide; Cyclic GMP; Drug Combinations; Enzyme Inhibitors; Hypercapnia;

1999
Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin.
    European journal of pharmacology, 2001, Apr-13, Volume: 417, Issue:3

    Topics: Animals; Arginine; Arterioles; Carbon Dioxide; Cromakalim; Hypercapnia; Indazoles; Ion Channel Gatin

2001
Compensatory role of NO in cerebral circulation of piglets chronically treated with indomethacin.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Bradykinin; Cardiovascular Agents; Cells, Cultured; Cerebr

2002