7-nitroindazole has been researched along with Epilepsy, Complex Partial in 2 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Epilepsy, Complex Partial: A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levetiracetam was given alone or in combination with 7-nitroindazole, a preferential inhibitor of neuronal nitric oxide synthase, or with L: -arginine, the precursor of nitric oxide synthesis." | 1.35 | In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs. ( Carletti, F; D'Agostino, S; Ferraro, G; Lonobile, G; Rizzo, V; Sardo, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sardo, P | 2 |
| D'Agostino, S | 1 |
| Rizzo, V | 1 |
| Carletti, F | 1 |
| Lonobile, G | 1 |
| Ferraro, G | 2 |
2 other studies available for 7-nitroindazole and Epilepsy, Complex Partial
| Article | Year |
|---|---|
In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs.
Topics: Animals; Anticonvulsants; Arginine; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.
Topics: Animals; Anticonvulsants; Arginine; Brain; Dentate Gyrus; Disease Models, Animal; Drug Interactions; | 2007 |